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Benders'dictionary of nutrition and food technology

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331nitric oxide (NO) Synthesised in most mammalian cells by theaction <strong>of</strong> nitric oxide synthetase (EC 1.14.13.39) on arginine.Itcauses vasodilatation <strong>and</strong> inhibits platelet aggregation (<strong>and</strong> sohas anticoagulant action), acting by cell surface receptors <strong>and</strong>intracellular guanylate cyclase (EC 4.6.1.2), leading to increasedformation <strong>of</strong> cyclic GMP. Before it was identified, NO was knownas the endothelium-derived relaxation factor.nitrites Found in many plant <strong>food</strong>s, since they are rapidly formedby the reduction <strong>of</strong> naturally occurring nitrate. Nitrite is theessential agent in preserving meat by pickling, since it inhibitsthe growth <strong>of</strong> Clostridia; it also combines with the myoglobin <strong>of</strong>meat to form the characteristic red nitrosomyoglobin.See also nitrosamines.nitrogen A gas comprising about 80% <strong>of</strong> the atmosphere; in<strong>nutrition</strong> the term ‘nitrogen’ is used to refer to ammonium salts<strong>and</strong> nitrates utilised as plant fertilisers; proteins <strong>and</strong> amino acidsas animal nutrients; <strong>and</strong> urea <strong>and</strong> ammonium salts as excretoryproducts.nitrogenase The enzyme (EC 1.18.6.1 or 1.19.6.1) in nitrogenfixingmicro-organisms that catalyses the reduction <strong>of</strong> N 2 toammonia. Irreversibly inactivated by oxygen.See also leghaemoglobin.nitrogen balance (N balance) The difference between the dietaryintake <strong>of</strong> nitrogen (mainly protein) <strong>and</strong> its excretion (as urea <strong>and</strong>other waste products). Healthy adults excrete the same amountas is ingested, <strong>and</strong> so are in nitrogen equilibrium. During growth<strong>and</strong> tissue repair (convalescence) the body is in positive Nbalance, i.e. ingestion is greater than loss <strong>and</strong> there is an increasein the total body pool <strong>of</strong> nitrogen (protein). In fevers, fasting <strong>and</strong>wasting diseases (see cachexia) the loss is greater than the intake<strong>and</strong> the individual is in negative balance; there is a net loss <strong>of</strong>nitrogen from the body.nitrogen conversion factor Factor by which total nitrogen content<strong>of</strong> a material (measured chemically, e.g. by the kjeldahl determination)is multiplied to determine the protein; depends on theamino acid composition <strong>of</strong> the proteins concerned. Wheat <strong>and</strong>most cereals 5.8, rice 5.95, soya 5.7, most legumes <strong>and</strong> nuts 5.3,milk 6.38, other <strong>food</strong>s 6.25. Errors arise if part <strong>of</strong> the nitrogen isnon-protein nitrogen. In mixtures <strong>of</strong> proteins, as in dishes <strong>and</strong>diets, the factor <strong>of</strong> 6.25 is used. Crude protein is defined as N ×6.25.nitrogen equilibrium See nitrogen balance.nitrogen-free extract (NFE) In the analysis <strong>of</strong> <strong>food</strong>s <strong>and</strong> animalfeedingstuffs, the fraction that contains the sugars <strong>and</strong> starchesplus small amounts <strong>of</strong> other materials.

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