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FICEP<br />

91172<br />

Reference Values:<br />

IMIPRAMINE AND DESIPRAMINE<br />

Total therapeutic concentration: 175-300 ng/mL<br />

Total toxic concentration: > or =300 ng/mL<br />

DESIPRAMINE ONLY<br />

Therapeutic concentration: 100-300 ng/mL<br />

Toxic concentration: > or =300 ng/mL<br />

Note: Therapeutic ranges are for specimens drawn at trough (ie, immediately before next scheduled<br />

dose). Levels may be elevated in non-trough specimens.<br />

Clinical References: 1. Wille SM, Cooreman SG, Neels HM, Lambert WE: Relevant issues in the<br />

monitoring and the toxicology of antidepressants. Crit Rev Clin Lab Sci 2008;45(1):25-89 2. Thanacoody<br />

HK, Thomas SH: Antidepressant poisoning. Clin Med 2003;3(2):114-118 3. Baumann P, Hiemke C,<br />

Ulrich S, et al: The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in<br />

psychiatry. Pharmacopsychiatry 2004;37(6):243-265<br />

Immune Complex Expanded Panel<br />

Reference Values:<br />

PEG IgG<br />

REFERENCE RANGE: < 3.5 mg/dL<br />

INTERPRETIVE CRITERIA:<br />

< 3.5 mg/dL Normal level<br />

> or = 3.5 mg/dL Elevated level<br />

The PEG method is both antigen and antibody non-specific<br />

and is based on the property of immune complexes to<br />

precipitate at low concentrations of PEG (2.5-3.5%). The<br />

PEG method will precipitate immune complexes of various<br />

sizes and composition as well as other macromolecules<br />

present in serum. Elevated serum IgG may cause a false<br />

positive increase in the PEG precipitate.<br />

<strong>Test</strong> Performed by: Focus Diagnostics, Inc<br />

5785 Corporate Avenue<br />

Cypress, CA 90630-4750<br />

Immune Complex, C1q<br />

REFERENCE RANGE: < or = 25.1 mcg Eq/mL<br />

<strong>Test</strong> Performed by: Quest Diagnostics Nichols Institute<br />

33608 Ortega Highway<br />

San Juan Capistrano, CA 92690-6130<br />

C3d Immune Complex<br />

REFERENCE RANGE: 0 – 8 mcg/mL<br />

<strong>Test</strong> Performed by: Quest Diagnostics Nichols Institute<br />

33608 Ortega Highway<br />

San Juan Capistrano, CA 92690-6130<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1005

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