Sorted By Test Name - Mayo Medical Laboratories

FDIRU
57280
FDM1
91592
ADNA
8178
Interpretation: Therapeutic concentration is 2.0 to 5.0 mcg/mL. Arrhythmias may occur at
concentrations 5.0
mcg/mL. Severe toxicity occurs with values > or =7.0 mcg/mL.
Reference Values:
Therapeutic: 2.0-5.0 mcg/mL
Toxic: > or =7.0 mcg/mL
Clinical References: 1. Valdes R JR, Jortani SA, Gheorghiade M: Standards of laboratory practice:
cardiac drug monitoring. National Academy of Clinical Biochemistry. Clin Chem 1998;44(5):1096-1109
2. Disopyramide In Physicianâ€s Desk Reference. November, 2009
Diuretic Screen, Urine
Reference Values:
Negative
Qualitative diuretic screen includes: benzthiazide, bumetanide, chlorothiazide, chlorthalidone,
furosemide, hydrochlorothiazide, hydroflumethiazide, and metolazone.
Test Performed By: Medtox Laboratories
402 W. County Road D
St. Paul, MN 55112
DM1 DNA
Reference Values:
A final report will be faxed under separate cover.
Test Performed by Athena Diagnostics
377 Plantation Street
Four Biotech Park
Worcester, MA 01605
DNA Double-Stranded (dsDNA) Antibodies, IgG, Serum
Clinical Information: Double-stranded (ds, native) DNA (dsDNA) antibodies of the IgG class are an
accepted criterion (American College of Rheumatology) for the diagnosis of systemic lupus
erythematosus (SLE).(1-3) dsDNA antibodies are detectable in approximately 85% of patients with
untreated SLE, and are rarely detectable in other connective tissue diseases. Weakly-positive results
caused by low-avidity antibodies to dsDNA are not specific for SLE and can occur in a variety of
diseases. Testing for IgG antibodies to dsDNA is indicated in patients who have a positive test for
antinuclear antibodies (ANA) along with signs and symptoms that are compatible with the diagnosis of
SLE.(2) If the ANA test is negative, there is no reason to test for antibodies to dsDNA.(2) The levels of
IgG antibodies to dsDNA in serum are known to fluctuate with disease activity in lupus erythematosus,
often increasing prior to an increase in inflammation and decreasing in response to therapy.(1,2) See
Connective Tissue Disease Cascade (CTDC) in Special Instructions.
Useful For: Evaluating patients with signs and symptoms consistent with lupus erythematosus (LE)
Monitoring patients with documented LE for flares in disease activity
Interpretation: A positive test result for double-stranded DNA (dsDNA) antibodies is consistent with
the diagnosis of systemic lupus erythematosus. A reference range study conducted at the Mayo Clinic
demonstrated that, within a cohort of healthy adults (n=120), no individuals between the ages of 18 and
60 (n=78) had detectable anti-dsDNA antibodies. Above the age of 60 (n=42), 11.9% of individuals (n=5)
had a borderline result for dsDNA antibodies and 4.8% of individuals (n=2) had a positive result.
Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 621