Sorted By Test Name - Mayo Medical Laboratories

FSCMS
57588
SGSS
81031
SSX2 encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.
EMBO J 1995;14:2333-2340 2. Clark J, Rocques PJ, Crew AJ, et al: Identification of novel genes, SYT
and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. Nat Genet
1994;7:502-508 3. Kawaii A, Wodruff J, Healey JH, et al: SYT-SSX gene fusion as a determinant of
morphology and prognosis in synovial sarcoma. N Engl J Med 1998;338:153-160 4. Jin L, Majerus J,
Oliveira A, et al: Detection of fusion gene transcripts in fresh-frozen and formalin-fixed
paraffin-embedded tissue sections of soft tissue sarcomas after laser capture microdissection and RT-PCR.
Diagn Mol Pathol 2003;12:224-230
Synthetic Cannabinoid Metabolites Screen - Expanded, Urine
Reference Values:
An interpretive report will be faxed or mailed under separate cover.
Test Performed by: NMS Labs
3701 Welsh Road
P.O. Box 433A
Willow Grove, PA 19090-0437
Synthetic Glucocorticoid Screen, Serum
Clinical Information: Synthetic glucocorticoids are widely used and have important clinical utility
both as anti-inflammatory and immunosuppressive agents. The medical use of these agents, as well as
their surreptitious use, can sometimes lead to a confusing clinical presentation. Patients exposed to these
steroids may present with clinical features of Cushing syndrome, but with suppressed cortisol levels and
evidence of hypothalamus-pituitary-adrenal axis suppression.
Useful For: Confirming the presence of listed synthetic glucocorticoids (see Interpretation) Confirming
the cause of secondary adrenal insufficiency This assay does not detect fluticasone propionate.
Interpretation: This test screens for and quantitates, if present, the following synthetic
glucocorticoids: betamethasone, budesonide, dexamethasone, fludrocortisone, flunisolide,
fluorometholone, megestrol acetate, methylprednisolone, prednisolone, prednisone, triamcinolone, and
triamcinolone acetonide. The presence of synthetic glucocorticoids in serum indicates current or recent
use of these compounds. Since several of these compounds exceed the potency of endogenous cortisol by
1 or more orders of magnitude, even trace levels may be associated with Cushingoid features.
Reference Values:
Negative
Cutoff concentrations
Betamethasone: 0.10 mcg/dL
Budesonide: 0.10 mcg/dL
Dexamethasone: 0.10 mcg/dL
Fludrocortisone: 0.10 mcg/dL
Flunisolide: 0.10 mcg/dL
Fluorometholone: 0.10 mcg/dL
Megestrol acetate: 0.10 mcg/dL
Methylprednisolone: 0.10 mcg/dL
Prednisolone: 0.10 mcg/dL
Prednisone: 0.10 mcg/dL
Triamcinolone: 0.30 mcg/dL
Triamcinolone acetonide: 0.10 mcg/dL
Values for normal patients not taking these synthetic glucocorticoids should be less than the cutoff
concentration (detection limit).
Clinical References: 1. Cave A, Arlett P, Lee E: Inhaled and nasal corticosteroids: factors affecting
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