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PARID<br />

9202<br />

OAP<br />

9216<br />

reported as "unclassified antineuronal IgG." If detected, newly identified autoantibody specificities may<br />

be reported. Complex patterns that include non-neuronal elements may be reported as "uninterpretable."<br />

Clinical References: 1. Lucchinetti CF, Kimmel DW, Lennon VA: Paraneoplastic and oncological<br />

profiles of patients seropositive for type 1 anti-neuronal nuclear antibody. Neurology 1998;50:652-657 2.<br />

Graus F, Vincent A, Pozo-Rosich P, et al: Anti-glial nuclear antibody: marker of lung cancer-related<br />

paraneoplastic neurological syndromes. J Neuroimmunol 2005;154(1-2):166-171 3. Pittock SJ,<br />

Lucchinetti CF, Lennon VA: Anti-neuronal nuclear autoantibody type 2: paraneoplastic accompaniments.<br />

Ann Neurol 2003;53(5):580-587 4. Chan KH, Vernino S, Lennon VA: ANNA-3 anti-neuronal nuclear<br />

antibody: marker of lung cancer-related autoimmunity. Ann Neurol 2001 September;50(3):301-311 5.<br />

Hetzel DJ, Stanhope CR, O'Neill BP, Lennon VA: Gynecologic cancer in patients with subacute<br />

cerebellar degeneration predicted by anti-purkinje cell antibodies and limited in metastatic volume. <strong>Mayo</strong><br />

Clin Proc 1990;65:1558-1563 6. Vernino S, Lennon VA: New Purkinje cell antibody (PCA-2): marker of<br />

lung cancer-related neurological autoimmunity. Ann Neurol 2000 March;47(3):297-305 7. Pittock SJ,<br />

Lucchinetti CF, Parisi JE, et al: Amphiphysin autoimmunity: paraneoplastic accompaniments. Ann Neurol<br />

2005;58(1):96-107 8. Yu Z, Kryzer TJ, Griesmann GE, et al: CRMP-5 neuronal autoantibody: marker of<br />

lung cancer and thymoma-related autoimmunity. Ann Neurol 2001 February;49(2):146-154<br />

Parasite Identification<br />

Clinical Information: Infectious diseases are spread by a variety of vectors. Identifying the vector<br />

and causative agent often involves visual examination of organisms.<br />

Useful For: Gross identification of parasites (eg, worms), arthropods (eg, insects, spiders), and suspect<br />

material passed in stool Identifying ticks, including Ixodes (carrier of Lyme disease)<br />

Interpretation: A descriptive report is provided.<br />

Reference Values:<br />

A descriptive report is provided.<br />

Parasitic Examination<br />

Clinical Information: Diarrhea, malnutrition, anemia, and intestinal obstruction are some of the<br />

consequences of infection with intestinal parasites. Protozoa may cause diarrhea and/or malabsorption by<br />

elaborating toxins or by adhering to or invading the mucosa or by unknown mechanisms.<br />

Cryptosporidiosis occurs as a self-limited moderate diarrhea in young children, especially daycare<br />

attendees and their relatives. Helminths (worms) may obstruct the intestine, cause blood loss, or interfere<br />

with the absorption of essential nutrients. Larvae or eggs may disseminate beyond the intestine and cause<br />

tissue destruction and provoke inflammation. Parasitic protozoa and helminths of various types also may<br />

inhabit the intestinal tracts of humans and animals without causing disease.<br />

Useful For: Detection and identification of parasites: included are Giardia, Entamoeba histolytica<br />

(amoeba), helminth eggs, protozoa, larval worms, and segments (proglottids) of tapeworms. See Parasitic<br />

Investigation of Stool Specimens Algorithm in Special Instructions for other diagnostic tests that may be<br />

of value in evaluating patients with diarrhea.<br />

Interpretation: A positive result indicates the presence of the parasite but does not necessarily indicate<br />

that it is the cause of any symptoms. Some strains of protozoa are nonpathogenic and some helminths<br />

cause little or no illness.<br />

Reference Values:<br />

Negative<br />

If positive, organism identified<br />

Clinical References: Garcia L, Bruckner D: Diagnostic <strong>Medical</strong> Parasitology. 3rd edition.<br />

Washington, DC, ASM Press, 1997<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1364

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