Sorted By Test Name - Mayo Medical Laboratories

EBVE
110090
lymphoproliferative syndromes, especially in patients who have undergone renal or bone marrow
transplantation and in those who have AIDS.
Useful For: The test is indicated for patients with malignant lesions of type 2 and 3 in whom NPC is
suspected; for example, patients with metastases to the cervical lymph nodes from an unknown primary
source.
Interpretation: Presence of IgA class antibody to the viral capsid antigen (VCA) of Epstein-Barr virus
(EBV) indicates active replication of EBV. High levels of IgA class antibody to the VCA supports the
clinical diagnosis of NPC. These antibodies are present in 84% of patients with type 2 NPC. IgA directed
against VCA is positive for type 1 carcinoma in only 16% of cases. The specificity of the test is such that
82% to 91% of healthy blood donors and patients who do not have NPC have negative responses.
Reference Values: