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Sorted By Test Name - Mayo Medical Laboratories

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AMOBS<br />

8325<br />

FAMOX<br />

80450<br />

FMAXN<br />

57245<br />

are established, the amniocyte cultures are sent to other laboratories, either within <strong>Mayo</strong> Clinic or to<br />

external sites, based on the specific testing requested.<br />

Reference Values:<br />

Not applicable<br />

Clinical References: Barch MJ, Knutsen T, Spurbeck JL: In The AGT Cytogenetics Laboratory<br />

Manual. 3rd edition, 1997<br />

Amobarbital, Serum<br />

Clinical Information: Amobarbital is an intermediate-acting barbiturate with hypnotic properties<br />

used in short-term treatment of insomnia and to reduce anxiety and provide sedation preoperatively. (1, 2)<br />

Amobarbital is administered by intravenous infusion or intramuscular injection. The duration of its<br />

hypnotic effect is about 6 to 8 hours. The drug distributes throughout the body, with a volume of<br />

distribution of 0.9 to 1.4 L/kg, and about 59% of a dose is bound to plasma proteins. Metabolism takes<br />

place in the liver primarily via hepatic microsomal enzymes. Its half-life is about 15 to 40 hours (mean: 25<br />

hours). Excretion occurs mainly in the urine. (2, 3)<br />

Useful For: Monitoring amobarbital therapy<br />

Interpretation: The therapeutic range of amobarbital is 1 to 5 mcg/mL, with toxicity typically<br />

associated with concentrations >10 mcg/mL. (2)<br />

Reference Values:<br />

Therapeutic concentration: 1.0-5.0 mcg/mL<br />

Toxic concentration: >10.0 mcg/mL<br />

Concentration at which toxicity occurs varies and should be interpreted in light of clinical situation.<br />

Clinical References: 1. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 10th<br />

edition. New York, McGraw-Hill Book Company, 2001 2. Teitz Textbook of Clinical Chemistry and<br />

Molecular Diagnostics. 4th edition. St. Louis, MO, Elsvier Saunders, 2006, pp 1091 3. Disposition of<br />

Toxic Drugs and Chemicals in Man. 7th edition. Edited by RC Baselt. Foster City, CA, Biomedical<br />

Publications, 2004, pp 1254<br />

Amoxapine (Asendinr) and 8-Hydroxyamoxapine<br />

Reference Values:<br />

Amoxapine No reference range provided<br />

8-Hydroxyamoxapine No reference range provided<br />

Combined Total 200 - 400 ng/mL<br />

<strong>Test</strong> Performed <strong>By</strong>:<br />

Medtox <strong>Laboratories</strong>, Inc.<br />

402 W. County Road D<br />

St. Paul, MN 55112<br />

Amoxicillin Level, BA<br />

Reference Values:<br />

AMOXICILLIN LEVEL mcg/mL<br />

Average peak levels (1-2 hrs post oral dosing)<br />

250 mg: 3.5-5.5 mcg/mL<br />

400 mg: 5.9 mcg/mL<br />

500 mg: 5.5-7.5 mcg/mL<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 122

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