Sorted By Test Name - Mayo Medical Laboratories

IGE
8159
FLCP
84190
features, response to therapy, and survival in a series of 53 cases. J Clin Oncol 1994;12(11):2398-2404 2.
Kyle RA, Katzmann JA: Immunochemical characterization of immunoglobulins. In Manual of Clinical
Laboratory Immunology. 5th edition. Edited by NR Rose, E Conway de Macario, JD Folds, et al:
Washington, DC, ASM Press,1997, pp 156-176 3. Tietz NW: In Clinical Guide to Laboratory Tests. 2nd
edition. Philadelphia, WB Saunders Company, 1990, p 325
Immunoglobulin E (IgE), Serum
Clinical Information: IgE antibodies mediate allergic diseases by sensitizing mast cells and
basophils to release histamine and other inflammatory mediators on exposure to allergens. Serum levels of
IgE are increased in many patients with allergic diseases, parasitic diseases, allergic bronchopulmonary
aspergillosis, and the rare hyper IgE syndrome.
Useful For: As an initial (screening) test for allergic disease
Interpretation: Serum levels of IgE greater than the mean +1 standard deviation (SD) for age suggest
the presence of allergic disease. Levels greater than the mean +2 SD strongly suggest the presence of
allergic disease.
Reference Values:
Results Reported in kU/L
Age Mean +1SD +2SD
0-6 weeks 0.6 2.3 8.8
7 weeks-3 months 1.0 4.1 17.0
4-6 months 1.8 7.3 30.0
7-9 months 2.6 10.0 39.0
10-23 months 3.2 13.0 53.0
2 years 5.7 23.0 93.0
3 years 8.0 32.0 128.0
4 years 10.0 40.0 160.0
5 years 12.0 48.0 192.0
6 years 14.0 56.0 224.0
7 years 16.0 63.0 248.0
8 years 18.0 71.0 280.0
9 years 20.0 78.0 304.0
10 years 22.0 85.0 328.0
Adults 13.2 41.0 127.0
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by
Laboratory Methods. 21st edition. New York, WB Saunders Company, 2007, pp 961-971
Immunoglobulin Free Light Chains, Serum
Clinical Information: The monoclonal gammopathies are characterized by a clonal expansion of
plasma cells that secrete a monoclonal immunoglobulin (Ig). The monoclonal Ig secreted by these cells
serves as a marker of the clonal proliferation, and the quantitation of monoclonal protein can be used to
monitor the disease course. The monoclonal gammopathies include multiple myeloma (MM), light chain
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