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Sorted By Test Name - Mayo Medical Laboratories

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FURBF<br />

57373<br />

RURCU<br />

89846<br />

urealyticum and Ureaplasma parvum at <strong>Mayo</strong> <strong>Medical</strong> <strong>Laboratories</strong>.<br />

Useful For: Rapid, sensitive, and specific identification of Ureaplasma urealyticum and Ureaplasma<br />

parvum from genitourinary, reproductive, and lower respiratory sources<br />

Interpretation: A positive PCR result for the presence of a specific sequence found within the<br />

Ureaplasma urealyticum and Ureaplasma parvum ureC gene indicates the presence of Ureaplasma<br />

urealyticum or Ureaplasma parvum DNA in the specimen. A negative PCR result indicates the absence of<br />

detectable Ureaplasma urealyticum and Ureaplasma parvum DNA in the specimen, but does not rule-out<br />

infection as false-negative results may occur due to the following; inhibition of PCR, sequence variability<br />

underlying the primers and/or probes, or the presence of Ureaplasma urealyticum or Ureaplasma parvum<br />

in quantities less than the limit of detection of the assay.<br />

Reference Values:<br />

Not applicable<br />

Clinical References: 1. Waites KB, Taylor-Robinson D: Mycoplasma and Ureaplasma. In Manual<br />

of Clinical Microbiology. 10th edition. Edited by J Versalovic. ASM Press, Washington, DC, 2011 2.<br />

Stellrecht KA, Woron AM, Mishrik NG, Venezia RA: Comparison of multiplex PCR assay with culture<br />

detection of genital mycoplasmas. J Clin Microbiol 2004;42:1528-1533 3. Kenny GE:<br />

Genital,mycoplasmas: Mycoplasma genitalium, Mycoplasma hominis, and Ureaplasma species. In<br />

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Edited by GL Mandell, et<br />

al. Churchill Livingstone, New York, 2008 4. Yoshida T, Maeda SI, Deguchi T, et al: Rapid detection of<br />

Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum<br />

organisms in genitourinary samples by PCR-microtiter plate hybridization assay. J Clin Microbiol<br />

2003;41:1850-1855 5. Cunningham SA, Shannon SK, Rosenblatt J, Patel R: Comparison of culture and<br />

rapid polymerase chain reaction detection of Mycoplasma hominis, Ureaplasma urealyticum and<br />

Ureaplasma parvum from genitourinary specimens. 48th Annual Infectious Diseases Society of America<br />

Meeting, 2010.<br />

Uric Acid, Body Fluid<br />

Reference Values:<br />

Units: mg/dL<br />

This test was performed using the Roche Modular P analyzer and Roche reagents. A reference interval<br />

has not been established for this analyte in body fluid samples.<br />

<strong>Test</strong> Performed by: ARUP <strong>Laboratories</strong><br />

500 Chipeta Way<br />

Salt Lake City, UT 84108<br />

Uric Acid, Random, Urine<br />

Clinical Information: Uric acid is the end-product of purine metabolism. It is freely filtered by the<br />

glomeruli and most is reabsorbed by the tubules. There is also active tubular secretion. Increased levels of<br />

uric acid in the urine usually accompany increased plasma uric acid levels unless there is a decreased<br />

excretion of uric acid by the kidneys. Urine uric acid levels reflect the amount of dietary purines and also<br />

endogenous nucleic acid breakdown. Acute uric acid nephropathy can cause acute renal failure due to uric<br />

acid precipitation within tubules. This is most commonly seen in patients with hematologic malignancies<br />

(eg, lymphoma, leukemia), often after acute lysis of cells by chemotherapy. Less commonly this may be<br />

seen with seizures, treatment of solid tumors, overproduction of uric acid in metabolic disorders such as<br />

Lesch-Nyhan syndrome or decreased uric acid reabsorption in the proximal nephron due to tubular<br />

disorder (Fanconi syndrome).<br />

Useful For: Differentiation of acute uric acid nephropathy from other causes of acute renal failure<br />

Patients who cannot collect a 24-hour specimen, typically small children, a uric acid creatinine ratio can<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1818

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