Sorted By Test Name - Mayo Medical Laboratories

BRM
8608
BRUGM
89476
0 Negative
1 0.35-0.69 Equivocal
2 0.70-3.49 Positive
3 3.50-17.4 Positive
4 17.5-49.9 Strongly positive
5 50.0-99.9 Strongly positive
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by
Laboratory Methods. 21st edition. Edited by McPherson RA, Pincus MR. WB Saunders, Publ, New York,
Chapter 53, Part VI, pp. 961-971, 2007
Bromide, Blood
Clinical Information: Bromides are ingested principally as sedatives. They are used outside the
United States to treat grand mal and focal epilepsy. Bromide shares the same volume of distribution as
chloride, competes with chloride for renal excretion, and has a blood half-life of 12 to 15 days. Signs of
acute toxicity include nausea, vomiting, and diarrhea. Manifestations of chronic toxicity can include
lethargy, fatigue, irritability, loss of appetite, tachypnea, skin pigmentation, hallucinations, ataxia, and
coma.
Useful For: Assessing possible toxicity
Interpretation: Therapeutic concentration: 1,000-2,000 mcg/mL Toxic concentration: > or =3,000
mcg/mL
Reference Values:
Therapeutic concentration: 1,000-2,000 mcg/mL
Toxic concentration: > or =3,000 mcg/mL
NIH Unit
Therapeutic concentration: 12.5-25.0 mmol/L
Toxic concentration: >27.5 mmol/L
Clinical References: Bowers GN Jr, Onoroski M: Hyperchloremia and the incidence of bromism in
1990 (editorial). Clin Chem 1990;36:1399-1403
Brucella Antibody Screen, IgG & IgM, Serum
Clinical Information: Worldwide, brucellosis remains a major disease in humans and domesticated
animals. Brucella infects goats (Brucella melitensis), cattle (Brucella abortus), swine (Brucella suis), and
dogs (Brucella canis).(1) The disease has a limited geographic distribution. Few cases occur in the United
States, with the bulk occurring in the Mediterranean region, Western Asia, and parts of Latin America and
Africa. Three species of Brucella commonly cause disease in humans: Brucella melitensis, Brucella suis,
and Brucella abortus. The acute disease often presents with fever, chills, and malaise; the chronic form
also causes abscesses in bone, brain, spleen, liver, and kidney.
Useful For: Evaluating patients with suspected brucellosis
Interpretation: In the acute stage of the disease there is an initial production of IgM antibodies,
followed closely by production of IgG antibodies. IgG-class antibodies may decline after treatment;
however, high levels of circulating IgG-class antibodies may be found without any active disease. Chronic
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