Sorted By Test Name - Mayo Medical Laboratories

FFTRM
90115
TMP
80146
SURM
80463
5 50.0-99.9 Strongly positive
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by
Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders
Company, 2007, Chapter 53, Part VI, pp 961-971
Trimethadione (Tridione) and Dimethadione
Reference Values:
Trimethadione (Tridione):
Reference Range: 3.0-42.0 ug/mL
Dimethadione Metabolite:
Reference Range: 300-800 ug/mL
Test Performed By:
Medtox Laboratories, Inc.
402 W. County Road D
St. Paul, MN 55112
Trimethoprim, Serum
Clinical Information: Trimethoprim is coadministered with sulfamethoxazole for prophylaxis or
treatment of bacterial infections. These agents are used to treat a variety of infections including
methicillin-resistant Staphylococcus aureus, and for prophylaxis in immunosuppressed patients such as
HIV-positive individuals. Trimethoprim has a wide therapeutic index and dose-dependent toxicity.
Trimethoprim accumulates in patients with renal failure. Therapeutic drug monitoring is not commonly
performed unless there are concerns about adequate absorption, clearance, or compliance. Accordingly,
routine drug monitoring is not indicated in all patients.
Useful For: Monitoring trimethoprim therapy to ensure drug absorption, clearance, or compliance
Interpretation: Most patients will display peak steady state serum concentrations >2.0 mcg/mL when
drawn at least 1 hour after an oral dose. Target concentrations may be higher, depending on the intent of
therapy.
Reference Values:
>2.0 mcg/mL
Clinical References: 1. Young T, Oliphant C, Araoyinbo I, Volmink J: Co-trimoxazole prophylaxis
in HIV: the evidence. S Afr Med J 2008April;98(4):258-259 2. Avdic E, Cosgrove S: Management and
control strategies for community-associated methicillin-resistant Staphylococcus aureus. Expert Opin
Pharmacother 2008 June;9(9):1463-1479 3. Kamme C, Melander A, Nilsson N: Serum and saliva
concentrations of sulfamethoxazole and trimethoprim in adults in children: relation between saliva
concentrations and in vitro activity against nasopharyngeal pathogens. Scand J Infect Dis
1983;15:107-113 4. Goodman, Gilman's: The Pharmacological Basis of Therapeutics. 11th edition.
McGraw-Hill Publishing, 2006, p 1112
Trimipramine (Surmontilr)
Reference Values:
Reference Range: 50-300 ng/mL
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