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Sorted By Test Name - Mayo Medical Laboratories

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FINTA<br />

91708<br />

FINTB<br />

91719<br />

BIL28<br />

61702<br />

circulating interferon-alpha<br />

Interferon-alpha is one of three species of interferon that<br />

possesses various biological properties including<br />

immunomodulating activity, anti-tumor activity and<br />

anti-viral activity. Elevated interferon-alpha levels are<br />

reportedly seen in viral disease, chronic fatigue-immune<br />

dysfunction syndrome, and some inflammatory diseases.<br />

This test was performed using a kit that has not been cleared<br />

or approved by the FDA. The analytical performance<br />

characteristics of this test have been determined by Focus<br />

Diagnostics. This test should not be used for diagnosis without<br />

confirmation by other medically established means.<br />

<strong>Test</strong> Performed by: Focus Diagnostics, Inc.<br />

5785 Corporate Avenue<br />

Cypress, CA 90630-4750<br />

Interleukin 1a<br />

Reference Values:<br />

25-150 pg/mL<br />

This test was performed using a kit that has not been cleared or<br />

approved by the FDA and is designated as research use only.<br />

The analytic performance characteristics of this test have been<br />

determined by Inter Science Institute. This test is not intended for<br />

diagnosis or patient management decisions without confirmation<br />

by other medically established means.<br />

<strong>Test</strong> Performed <strong>By</strong>: Interscience Institute<br />

944 West Hyde Park Blvd<br />

Inglewood, CA 90302<br />

Interleukin 1b<br />

Reference Values:<br />

Up to 1.00 pg/mL<br />

<strong>Test</strong> Performed <strong>By</strong>: Interscience Institute<br />

944 West Hyde Park Blvd<br />

Inglewood, CA 90302<br />

Interleukin 28B (IL28B) Polymorphism (rs12979860), Blood<br />

Clinical Information: Individuals with hepatitis C virus (HCV) genotype 1 infections have variable<br />

responses to treatment with pegylated-interferon and ribavirin combination therapy. Some individuals will<br />

respond to treatment with sustained viral response, while other patients have poor response and fail to<br />

achieve sustained viral clearance. Response to pegylated-interferon and ribavirin combination therapy in<br />

HCV genotype 1-infected individuals has been found to be closely associated with a single-nucleotide<br />

polymorphism (SNP), designated rs12979860, located 3 kilobases upstream from the interleukin 28B<br />

gene locus (IL28B) present on human chromosome 19. HCV genotype 1-infected individuals with the CC<br />

genotype, as compared to either the CT or TT genotypes, of this SNP in IL28B have approximately 2- to<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1041

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