Sorted By Test Name - Mayo Medical Laboratories

FALCO
90084
ALS
8363
ALDNA
15150
the Treatment of Alcohol use Disorders". Substance Abuse Treatment advisory, volume 5, issue 4,
September 2006.
Alcohol, Methyl
Reference Values:
No reference range provided.
Methanol (methyl alcohol) concentrations >3 mg/dL are
potentially toxic.
Test Performed By:
Medtox Laboratories, Inc.
402 W. County Road D
St. Paul, MN 55112
Aldolase, Serum
Clinical Information: Aldolase is necessary for glycolysis in muscle as a "rapid response" pathway
for production of adenosine triphosphate, independent of tissue oxygen. Aldolase catalyses the conversion
of fructose 1,6-diphosphate into dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, an
important reaction in the glycolytic breakdown of glucose to lactate in muscle. Aldolase is a tetramer
whose primary structure depends upon the tissue from which it was synthesized (liver, muscle, brain). The
brain form of aldolase has, because of its preponderance in white cells, been suggested to be a leukemia
marker, but this is not confirmed. Elevated values are found in muscle diseases, such as Duchenne
muscular dystrophy, dermatomyositis, polymyositis, and limb-girdle dystrophy.
Useful For: Detection of muscle disease
Interpretation: The highest levels of aldolase are found in progressive (Duchenne) muscular
dystrophy. Lesser elevations are found in dermatomyositis, polymyositis, and limb-girdle dystrophy. In
dystrophic conditions causing hyperaldolasemia, the increase in aldolase becomes less dramatic as muscle
mass decreases. Reference (normal) values are observed in polio, myasthenia gravis, and multiple
sclerosis. Aldolase increases in myocardial infarction in a time pattern similar to the aspartate
aminotransferase. Increases are also associated with acute viral hepatitis, but levels are normal or slightly
elevated in chronic hepatitis, portal cirrhosis, and obstructive jaundice. Elevations may also be seen with
gangrene, prostate tumors, trichinosis, some carcinomas metastatic to the liver, some chronic leukemias,
some blood dyscrasias, and delirium tremens.
Reference Values:
0-16 years: or =17 years: