Sorted By Test Name - Mayo Medical Laboratories

FINS
81728
INS
8664
Reference Values:
< or =0.02 nmol/L
Reference values apply to all ages.
Clinical References: 1. Schernthaner G: Immunogenicity and allergenic potential of animal and
human insulins. Diabetes Care 1993;3:155-165 2. Lernmark A: Type 1 diabetes. Clin Chem
1999;45:1331-1338 3. Eisenbarth GS, Jeffery J: The natural history of type 1A diabetes. Arq Bras
Endocrinol Metabol 2008 Mar;52(2):146-155
Insulin, Free, Serum
Clinical Information: Insulin is a hormone produced by the beta cells of the pancreas. Free insulin
measurements should be comparable to routine insulin values in the absence of insulin antibodies. Insulin
autoantibodies may develop, however, in patients who have been injecting non human insulin for
treatment of insulin-dependent diabetes. These antibodies will directly bind to insulin, making it
unavailable for metabolic activity. The antibodies may also adversely affect the binding characteristics of
insulin in immunoassays, making reliable quantitation difficult.
Useful For: Management of diabetes mellitus when the patient has known insulin autoantibodies
Interpretation: During prolonged fasting, when the patient's glucose is reduced to