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Sorted By Test Name - Mayo Medical Laboratories

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B2OSH<br />

300245<br />

B2MC<br />

60546<br />

Beta-2-Microglobulin (B-2-M), for Occupational Monitoring,<br />

Urine<br />

Clinical Information: Beta-2-microglobulin is a low-molecular-weight protein that forms the light<br />

chain component of class I histocompatibility (HLA [human leukocyte antigen]) antigens. Increased urine<br />

levels are seen in proximal tubular renal damage due to a variety of causes, including cadmium, mercury,<br />

lithium, or aminoglycoside toxicity; pyelonephritis; and Balkan nephropathy, a chronic interstitial<br />

nephritis of unknown etiology.<br />

Useful For: Evaluation of renal tubular damage Monitoring exposure to cadmium and mercury<br />

Interpretation: Increased excretion is consistent with renal tubular damage. Beta-2-microglobulin<br />

excretion is increased 100 to 1,000 times normal levels in cadmium-exposed workers.<br />

Reference Values:<br />

CREATININE<br />

Not established<br />

BETA-2-MICROGLOBULIN<br />

< or =300 mcg/L<br />

BETA-2-MICROGLOBULIN STANDARDIZED<br />

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