Sorted By Test Name - Mayo Medical Laboratories

CRP
9731
HSCRP
82047
Adults 24 h: 43 - 175
C-Peptide/Creatinine Ratio (ug/g)
Adults 24 h: 37 - 113
Overnight fasting: 10 - 50
3 h post prandial: 29 - 169
24 hr Creatinine, Urine (mg/24h)
Males 1000 - 2000
Females 800 - 1800
Creatinine, Urine (mg/dL)
Test Performed by: Esoterix Endocrinology
4301 Lost Hills Road
Calabasas Hills, CA 91301
C-Reactive Protein (CRP), Serum
Clinical Information: C-reactive protein (CRP) is 1 of the most sensitive acute-phase reactants for
inflammation. CRP is synthesized by the liver and consists of 5 identical polypeptide chains that form a
5-membered ring with a molecular weight of 120,000 daltons. CRP levels can increase dramatically
(100-fold or more) after severe trauma, bacterial infection, inflammation, surgery, or neoplastic
proliferation. CRP has been used to assess activity of inflammatory disease, to detect infections after
surgery, to detect transplant rejection, and to monitor these inflammatory processes.
Useful For: Detecting systemic inflammatory processes Detecting infection and assessing response to
antibiotic treatment of bacterial infections Differentiating between active and inactive disease forms with
concurrent infection
Interpretation: Elevated values are consistent with an acute inflammatory process.
Reference Values:
< or =8.0 mg/L
Clinical References: Tietz NW, Burtis CA, Ashwood ER: In Tietz Textbook of Clinical Chemistry.
Third edition. Edited by CA Burtis, ER Ashwood. Philadelphia, WB Saunders Company, 1999
C-Reactive Protein, High Sensitivity, Serum
Clinical Information: C-reactive protein (CRP) is 1 of the most sensitive acute-phase reactants.
Plasma CRP levels can increase dramatically (100-fold or more) after severe trauma, bacterial infection,
inflammation, surgery, or neoplastic proliferation. Measurement of CRP has been used historically to
assess activity of inflammatory disease, to detect infections after surgery, to detect transplant rejection,
and to monitor these inflammatory processes. While assays for CRP have been available for many years,
the traditional assays lack the sensitivity to measure basal levels of CRP. In the mid-1990s, more sensitive
methods for measurement of CRP were introduced. These methods, referred to as high sensitivity CRP
(hs-CRP), can accurately measure basal levels of CRP throughout the currently accepted cardiovascular
risk assessment range (0.20-10.0 mg/L). These hs-CRP assays were used to assess outcomes in patients
with unstable angina and showed that hs-CRP values in the upper tertile (>3.0 mg/L) were associated with
increased risk of developing myocardial infarction (1,2). Data from prospective studies monitoring
hs-CRP in apparently healthy populations also has been published. All prospective studies reported to
date have been positive, with adjusted relative risks of developing cardiovascular disease or ischemic
events ranging from 2.3 to 4.8 in the highest quartile or quintile of data versus the lowest quartile or
quintile (3-6). It also has been shown that hs-CRP is additive with total cholesterol, LDL and HDL, as
well as the Framingham 10-year risk score, with respect to risk prediction (7-8). More aggressive
treatment strategies may be pursued in patients determined to be at increased risk by hs-CRP values.
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