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ABID2<br />

8988<br />

ABSCM<br />

8956<br />

Anti-Phosphatidylethanolamine IgG<br />

Normal 0.0 - 10.0<br />

Equivocal 10.1 - 20.0<br />

Elevated > 20.0<br />

Anti-Phosphatidylethanolamine IgM<br />

Normal 0.0 - 10.0<br />

Equivocal 10.1 - 20.0<br />

Elevated > 20.0<br />

<strong>Test</strong> Performed by:<br />

Cambridge Biomedical Inc.<br />

1320 Soldiers Field Road<br />

Boston, MA 02135<br />

Antibody Identification, Erythrocytes<br />

Clinical Information: After exposure to foreign red blood cells via transfusion or pregnancy, some<br />

people form antibodies which are capable of the destruction of transfused red cells or of fetal red cells in<br />

utero. It is important to identify the antibody specificity in order to assess the antibody's capability of<br />

causing clinical harm and, if necessary, to avoid the antigen on transfused red blood cells.<br />

Useful For: Assessing positive pretransfusion antibody screens, transfusion reactions, hemolytic<br />

disease of the newborn, and autoimmune hemolytic anemias<br />

Interpretation: Specificity of alloantibodies will be stated. The patient's red blood cells will be typed<br />

for absence of the corresponding antigen(s) or as an aid to identification in complex cases. A consultation<br />

service is offered, at no charge, regarding the clinical relevance of red cell antibodies.<br />

Reference Values:<br />

Negative<br />

If positive, antibodies will be identified and corresponding special red cell antigen typing on patient's red<br />

blood cells will be performed. A consultation service is offered, at no charge, regarding the clinical<br />

relevance of red cell antibodies.<br />

Clinical References: Technical Manual. Bethesda, MD, American Association of Blood Banks<br />

Antibody Screen, Erythrocytes<br />

Clinical Information: Transfusion and pregnancy are the primary means of sensitization to red cell<br />

antigens. In a given population, 2% to 4% of the general population possess irregular red cell<br />

alloantibodies. Such antibodies may cause hemolytic disease of the newborn or hemolysis of transfused<br />

donor red blood cells. Autoantibodies react against the patient's own red cells as well as the majority of<br />

cells tested. Autoantibodies can be clinically benign or can hemolyze the patient's own red blood cells,<br />

such as in cold agglutinin disease or autoimmune hemoyltic anemia.<br />

Useful For: Detection of allo- or autoantibodies directed against red blood cell antigens in the settings<br />

of pretransfusion testing Evaluation of transfusion reactions Evaluation of hemolytic anemia<br />

Interpretation: A positive result (antibody detected) necessitates antibody identification to establish<br />

the specificity and clinical significance of the antibody detected. Negative–no antibody detected.<br />

Reference Values:<br />

Negative<br />

If positive, antibody identification will be performed.<br />

Clinical References: Technical Manual. 14th edition. Edited by RH Walker. Bethesda, MD,<br />

American Association of Blood Banks, 2002, pp 379-418<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 147

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