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Sorted By Test Name - Mayo Medical Laboratories

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FLIPR<br />

90347<br />

LPS<br />

8328<br />

BFLAC<br />

34622<br />

LPSC<br />

8053<br />

Lipase, Random Urine<br />

Reference Values:<br />

Adult: 4 U/L or less<br />

<strong>Test</strong> Performed <strong>By</strong>: Quest Diagnostics Nichols Institute<br />

33608 Ortega Highway<br />

San Juan Capistrano, CA 92690-6130<br />

Lipase, Serum<br />

Clinical Information: Lipases are enzymes that hydrolyze glycerol esters of long-chain fatty acids<br />

and produce fatty acids and 2-acylglycerol. Bile salts and a cofactor, colipase, are required for full<br />

catalytic activity and greatest specificity. The pancreas is the primary source of serum lipase. Both lipase<br />

and colipase are synthesized in the pancreatic acinar cells and secreted by the pancreas in roughly<br />

equimolar amounts. Lipase is filtered and reabsorbed by the kidneys. Pancreatic injury results in increased<br />

serum lipase levels.<br />

Useful For: Investigating pancreatic disorders, usually pancreatitis<br />

Interpretation: In pancreatitis, lipase becomes elevated at about the same time as amylase (in 4-8<br />

hours). But lipase may rise to a greater extent and remain elevated much longer (7-10 days) than amylase.<br />

Elevations 2 to 50 times the upper reference have been reported. The increase in serum lipase is not<br />

necessarily proportional to the severity of the attack. Normalization is not necessarily a sign of resolution.<br />

In acute pancreatitis, normoamylasemia may occur in up to 20% of such patients. Likewise, the existence<br />

of hyperlipemia may cause a spurious normoamylasemia. For these reasons, it is suggested that the 2<br />

assays complement and not exclude each other, and that both enzymes should be assayed.<br />

Reference Values:<br />

> or =16 years: 10-73 U/L<br />

Reference values have not been established for patients that are 110 mg/dL is highly suggestive of a chylous effusion.<br />

Reference Values:<br />

Not applicable<br />

Clinical References: 1. Staats BA, Eleffson RD, Budahn LL, et al: The Lipoprotein Profile of<br />

Chylous and Nonchylous Pleural Effusions. <strong>Mayo</strong> Clin Proc 1980;55:700-704 2. Laterre PF, Dugernier T,<br />

Reynaert MS: Chylous ascites: diagnosis, causes and treatment. Acta Gastroenterol 2000;63:260-263<br />

Lipid Panel<br />

Clinical Information: Cardiovascular disease is the number 1 cause of death in the United States<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1112

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