Sorted By Test Name - Mayo Medical Laboratories

RB
8172
ROSC
80262
1 0.35-0.69 Equivocal
2 0.70-3.49 Positive
3 3.50-17.4 Positive
4 17.5-49.9 Strongly positive
5 50.0-99.9 Strongly positive
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by
Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders
Company, 2007, Chapter 53, Part VI, pp 961-971
Rubella Antibodies, IgG, Serum
Clinical Information: Primary postnatal rubella infection (German or 3-day measles) is typically a
mild, self-limiting disease characterized by a maculopapular rash, fever, malaise, and lymphadenopathy.
Conversely, primary prenatal rubella infections may have devastating results. In utero infections may
severely damage the fetus, particularly if the infection occurs during the first 4 months of gestation.
Congenitally infected infants may exhibit 1 or more defects including congenital heart disease and mental
retardation. Prior to the introduction of the rubella vaccines, approximately 15% of childhood
sensorineural deafness and 2% of congenital heart defects were attributed to congenital rubella infection
in both the United States (US) and the United Kingdom. During the epidemic of 1962 to 1965, rubella
infections during pregnancy were estimated to have caused 30,000 stillbirths and 20,000 malformed
infants in the US. The US rubella vaccination program, which calls for vaccination of all children, has
significantly reduced the incidence of rubella. A total of 9 cases of rubella were reported to the CDC in
2004, and only 4 cases of congenital rubella syndrome were reported between 2001 and 2004.(3) Due to
the success of the national vaccination program, rubella is no longer considered endemic in the US
(cdc.gov/rubella).
Useful For: Determination of rubella immune status
Interpretation: Approximately 80% to 90% of the United States (US) adult population shows
serologic evidence of immunity to rubella. The rubella vaccine is recommended for all children, as well as
nonimmune adolescents and adults (particularly females) unless it is specifically contraindicated. Due to
the national vaccination program, the majority of the US population will be positive for rubella IgG. A
positive result indicates either prior exposure to the virus or response to vaccination. The presence of
rubella IgG suggests immunity against rubella.
Reference Values:
Negative
Clinical References: 1. Yelland MJ: Rubella immune status in general practice. Aust Fam Physician
1989;18:1279-1281;1284-1285 2. Recommendation of the Immunization Practices Advisory Committee:
Centers for Disease Control Morbidity and Mortality Weekly Report 1981;30:37-47 3. Achievements in
Public Health: elimination of rubella and congenital rubella syndrome – United States, 1969-2004:
Centers for Disease Control Morbidity and Mortality Weekly Report, March, 2005;54(11):279-282
Rubeola (Measles) Antibodies Screen, IgG, Serum
Clinical Information: Measles (rubeola) virus is a member of the family paramyxoviridae, which
also includes mumps, respiratory syncytial virus, and parainfluenza viruses. Clinical infection with
measles virus is characterized by a prodromal phase of high fever, cough, coryza, conjunctivitis, malaise,
and Koplik's spots on the buccal mucosa. An erythematous rash then develops behind the ears and over
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