Sorted By Test Name - Mayo Medical Laboratories

MOLUC
89474
accumulation). Serum molybdenum concentrations are likely to be increased above the reference range in
patients with metallic joint prosthesis. Prosthetic devices produced by Depuy Company, Dow Corning,
Howmedica, LCS, PCA, Osteonics, Richards Company, Tricon, and Whiteside, typically are made of
chromium, cobalt, and molybdenum. This list of products is incomplete, and these products change
occasionally; see prosthesis product information for each device for composition details.
Useful For: Monitoring of parenteral nutrition. Monitoring metallic prosthetic implant wear. As an
indicator of molybdenum cofactor disease.
Interpretation: Prosthesis wear is known to result in increased circulating concentrations of metal
ions.(5-7) Serum concentrations >10 ng/mL in a patient with molybdenum-based implant suggest
significant prosthesis wear. Increased serum trace element concentrations in the absence of corroborating
clinical information do not independently predict prosthesis wear or failure. Serum molybdenum 400 mcg/day. Molybdenum interferes with copper uptake; molybdenum toxicity is
predominantly due to copper deficiency (hypochromic anemia and neutropenia) and inhibition of xanthine
oxidase (uric acid accumulation). Urine molybdenum concentrations are likely to be increased above the
reference range in patients with metallic joint prosthesis. Prosthetic devices produced by Zimmer
Company and Johnson and Johnson typically are made of aluminum, vanadium, and titanium. Prosthetic
devices produced by Depuy Company, Dow Corning, Howmedica, LCS, PCA, Osteonics, Richards
Company, Tricon, and Whiteside typically are made of chromium, cobalt, and molybdenum. This List of
products is incomplete, and these products change occasionally; see prothesis product information for
each device for composition details.(4-5)
Useful For: Monitoring of parenteral nutrition Monitoring metallic prosthetic implant wear As an
indicator of molybdenum cofactor disease
Interpretation: Molybdenum excretion rates are variable and related to dietary intake. Evaluation of
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