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Sorted By Test Name - Mayo Medical Laboratories

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FCLIN<br />

80143<br />

PCLLM<br />

20437<br />

Reference Values:<br />

Class IgE kU/L Interpretation<br />

0 Negative<br />

1 0.35-0.69 Equivocal<br />

2 0.70-3.49 Positive<br />

3 3.50-17.4 Positive<br />

4 17.5-49.9 Strongly positive<br />

5 50.0-99.9 Strongly positive<br />

6 > or =100 Strongly positive Reference values<br />

apply to all ages.<br />

Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by<br />

Laboratory Methods. 21st edition. Edited by McPherson RA, Pincus MR. WB Saunders, Publ, New York,<br />

Chapter 53, Part VI, pp. 961-971, 2007<br />

Clindamycin Level, BA<br />

Reference Values:<br />

Peak serum level (avg)<br />

150 mg oral dose: 2.5 mcg/mL<br />

Trough serum level (avg):<br />

150 mg oral, 6 hrs: 5.4 mcg/mL<br />

Peak serum level (avg)<br />

300 mg IV, 3 hrs: 5.4 mcg/mL<br />

Any undisclosed antimicrobials might affect the results.<br />

<strong>Test</strong> Performed <strong>By</strong>: Focus Diagnostics, Inc.<br />

5785 Corporate Ave.<br />

Cypress, CA 90630-4750<br />

CLL Monitoring, MRD Detection FLIP, see #60490<br />

Clinical Information: Chronic lymphocytic leukemia (CLL) is a low-grade, B-cell neoplasm that is<br />

the most common leukemia detected in the western world. It is a disease primarily of adults and may<br />

present as a lymphocytosis, be detected as part of a lymphadenopathy evaluation, or be found incidentally<br />

in an otherwise asymptomatic patient. The diagnosis of CLL is based on a combination of morphologic<br />

features showing primarily small lymphoid cells with coarse chromatin and scant cytoplasm and an<br />

immunophenotype of clonal B-cells with dim immunoglobulin, dim CD20, and coexpression of CD5 and<br />

CD23. New therapeutic approaches in CLL have been increasingly successful with some patients showing<br />

no or only very minimal residual disease (MRD) in their peripheral blood or bone marrow specimens<br />

following a therapeutic course. Immunophenotyping studies are necessary as morphologic features are not<br />

sufficient to detect MRD. The absence of MRD is an important prognostic indicator in these patients.<br />

Useful For: Confirming the presence or absence of minimal residual disease in patients with known<br />

chronic lymphocytic leukemia who are either post-chemotherapy or post-bone marrow transplantation<br />

Interpretation: An interpretive report for presence or absence of minimal residual disease (MRD) for<br />

chronic lymphocytic leukemia (CLL) is provided. Individuals without CLL should not have detectable<br />

clonal B-cells in the peripheral blood or bone marrow. Patients who have detectable MRD by this assay<br />

are considered to have residual CLL disease.<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 479

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