Sorted By Test Name - Mayo Medical Laboratories

SAM
9049
FEHA
91932
Interpretation: Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased
likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be
responsible for eliciting signs and symptoms. The level of IgE antibodies in serum varies directly with the
concentration of IgE antibodies expressed as a class score or kU/L.
Reference Values:
Class IgE kU/L Interpretation
0 Negative
1 0.35-0.69 Equivocal
2 0.70-3.49 Positive
3 3.50-17.4 Positive
4 17.5-49.9 Strongly positive
5 50.0-99.9 Strongly positive
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by
Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders
Company, 2007, Chapter 53, Part VI, pp 961-971
Entamoeba histolytica Antibody, Serum
Clinical Information: Amebiasis is an infection by the protozoan parasite, Entamoeba histolytica.
The infection is acquired by ingestion of cysts in fecally contaminated food or water; excystation and
infection occur in the large intestine. After excystation, trophozoites attach to the intestinal wall and
liberate extracellular enzymes which enable invasion of the mucosa and spread to other organs, especially
the liver and lung where abscesses develop. Amebiasis (or amebic dysentery) can cause bloody diarrhea
accompanied by fever and prostration. Leukocytes, WBCs, and RBCs are found in the stools. Liver
abscess can develop several weeks to months later producing hepatomegaly and fever. Pathogenic
(Entamoeba histolytica) and nonpathogenic (Entamoeba dispar) species of Entamoeba occur.
Additionally, some of those infected with pathogenic strains are asymptomatic cyst carriers. Intestinal
amebiasis should be diagnosed by detected Entamoeba histolytica in stool specimens.
Useful For: As an adjunct in the diagnosis of extraintestinal amebiasis, especially liver abscess
Serology may be particularly useful in supporting the diagnosis of amebic liver abscess in patients
without a definite history of intestinal amebiasis and who have not spent substantial periods of time in
endemic areas
Interpretation: A positive result suggests current or previous infection with Entamoeba histolytica.
Since pathogenic and nonpathogenic species of Entamoeba cannot be differentiated microscopically,
some authorities believe a positive serology indicates the presence of the pathogenic species (ie,
Entamoeba histolytica).
Reference Values:
Expected values: negative
Clinical References: Bruckner DA: Amebiasis. Clin Microbiol Rev 1992;5:356-369
Entamoeba histolytica Antigen, EIA
Reference Values:
Reference Range: Negative
Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 670