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PAIN
86328
drugs of abuse. Opiate confirmation is performed on all specimens by liquid chromatography mass
spectrometry(LC-MS/MS). This profile uses immunoassay testing for drugs of abuse by class. All
positive screening results are confirmed by gas chromatography/mass spectrometry (GC/MS).
Useful For: Detection and identification of drugs of abuse This test is intended to be used in a setting
where the identification of the drug is required.
Interpretation: A positive result derived by this testing indicates that the patient has been exposed in
the recent past to the drugs identified. Positive results are definitive. A detailed discussion of each drug
detected is beyond the scope of this text. Each report will indicate the drugs identified. If a clinical
interpretation is required, please contact Mayo Laboratory Inquiry.
Reference Values:
Negative for drugs of abuse
EMIT Screening cutoff concentration:
Amphetamines: 500 ng/mL
Barbiturates: 200 ng/mL
Benzodiazepines: 200 ng/mL
Cocaine (benzoylecgonine-cocaine metabolite): 150 ng/mL
Ethanol: 10 mg/dL
Methadone: 300 ng/mL
Opiates: 300 ng/mL
Phencyclidine: 25 ng/mL
Propoxyphene: 300 ng/mL
Tetrahydrocannabinol carboxylic acid: 50 ng/mL
This report is intended for use in clinical monitoring and management of patients. It is not intended for
use in employment-related drug testing.
Clinical References: 1. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. Tenth
edition. New York, McGraw-Hill Professional, 2001 2. Porter WF: Clinical toxicology. In Teitz Textbook
of Clinical Chemistry and Molecular Diagnostics. Fourth edition. St Louis, MO, Elsevier Saunders, 2006
3. Principles of Forensic Toxicology. Second edition. Washington DC, AACC Press, 2003, p 385
Pain Clinic Survey 10, Urine
Clinical Information: This assay was designed to test for and confirm by gas chromatography-mass
spectrometry (GC-MS) the following: -Amphetamines -Barbiturates -Benzodiazepines -Cocaine
-Methadone -Phencyclidine -Propoxyphene -Opiates -Tetrahydrocannabinol This test uses the simple
screening technique described under IDOAU/8248 Drug Abuse Survey, Urine, which involves
immunologic testing for drugs by class. Oxycodone is not detected well with the opiate screening assay;
therefore, OPATU/8473 Opiates, Urine is included to detect this drug. All positive screening results are
confirmed by GC-MS, and quantitated, before a positive result is reported.
Useful For: Detecting drug use involving amphetamines, barbiturates, benzodiazepines, cocaine,
methadone, opiates, phencyclidine, propoxyphene, and tetrahydrocannabinol This test is intended to be
used in a setting where the test results can be used to make a definitive diagnosis.
Interpretation: A positive result derived by this testing indicates that the patient has used 1 of the
drugs detected by this technique in the recent past. See individual tests (eg, AMPHU/8257
Amphetamines, Urine) for more information. For information about drug testing, including estimated
detection times, see Drugs of Abuse Testing at
http://www.mayomedicallaboratories.com/articles/drug-book/index.html Creatinine and specific gravity
are measured as indicators of specimen dilution.
Reference Values:
Negative
Screening cutoff concentrations
Amphetamines: 500 ng/mL
Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 1356