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Sorted By Test Name - Mayo Medical Laboratories

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89027<br />

KIDBN<br />

82619<br />

Reference Values:<br />

Reporting limit determined each analysis<br />

Synonym(s): Nizoral<br />

Peak plasma levels of 5.4 +/- 1.7 mcg/mL occurred at<br />

approximately 1 hour following a single 200 mg dose and peak<br />

plasma levels of 22 +/- 3 mcg/mL occurred at approximately<br />

2 hours following a single 800 mg dose of ketoconazole.<br />

<strong>Test</strong> Performed by: NMS Labs<br />

3701 Welsh Road<br />

P.O. Box 433A<br />

Willow Grove, PA 19090-0437<br />

Ki-67(MIB-1), Quantitative Immunohistochemistry, Automated<br />

Clinical Information: Ki-67(MIB-1 clone) is a monoclonal antibody that reacts with cells<br />

undergoing DNA synthesis by binding to the Ki-67 antigen, a marker known to be expressed only in<br />

proliferating cells. <strong>By</strong> measuring the amount of tumor cells expressing Ki-67, an estimate of DNA<br />

synthesis can be determined. Studies suggest that Ki-67(MIB-1) analysis of paraffin-embedded tissue<br />

specimens may provide useful prognostic information in various tumor types.<br />

Useful For: Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients<br />

diagnosed with breast or prostate carcinoma<br />

Interpretation: Results will be reported as a percentage of tumor cells staining positive for<br />

Ki-67(MIB-1). Quantitative Ki-67(MIB-1) results should be interpreted within the clinical context for<br />

which the test was ordered. For prostate biopsy cancer specimens: when this test is ordered in conjunction<br />

with digital image analysis, 80948 DNA Ploidy by Digital Image Analysis (DIA), Paraffin Block,<br />

Ki-67(MIB-1) results are reported as a low (

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