Sorted By Test Name - Mayo Medical Laboratories

TCIPF
60590
3-5 months: 170-830 cells/mcL*
6-11 months: 160-950 cells/mcL*
12-23 months: 180-920 cells/mcL*
2-5 years: 130-720 cells/mcL*
6-11 years: 100-480 cells/mcL*
12-17 years: 70-480 cells/mcL*
18-55 years: 101-678 cells/mcL
>55 years: 110-657 cells/mcL
Helper Cells (CD4)
0-2 months: 1,600-4,000 cells/mcL*
3-5 months: 1,800-4,000 cells/mcL*
6-11 months: 1,400-4,300 cells/mcL*
12-23 months: 1,300-3,400 cells/mcL*
2-5 years: 700-2,200 cells/mcL*
6-11 years: 650-1,500 cells/mcL*
12-17 years: 530-1,300 cells/mcL*
18-55 years: 424-1,509 cells/mcL
> 55 years: 430-1513 cells/mcL
Suppressor Cells (CD8)
0-2 months: 560-1,700 cells/mcL*
3-5 months: 590-1,600 cells/mcL*
6-11 months: 500-1,700 cells/mcL*
12-23 months: 620-2,000 cells/mcL*
2-5 years: 490-1,300 cells/mcL*
6-11 years: 370-1,100 cells/mcL*
12-17 years: 330-920 cells/mcL*
18-55 years: 169-955 cells/mcL
>55 years: 101-839 cells/mcL
LYMPHOCYTE RATIO
H/S ratio: > or = 1.0
*Shearer WT, Rosenblatt HM, Gelman RS, et al: Lymphocyte subsets in healthy children from birth
through 18 years of age: The Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol
2003;112(5):973-980
Clinical References: 1. Mandy F, Nicholson J, McDougal J: CBD: Guidelines for performing
single-platform absolute CD4+ T-cell determinations with CD45 gating for persons infected with human
immunodeficiency virus. Center for Disease Control and Prevention. MMWR Morb Mortal Wkly Rep
2003;52:1-13 2. Centers for Disease Control: 1997 Revised guidelines for performing CD4+ T-cell
determinations in persons infected with human immunodeficiency virus (HIV) MMWR 46 no RR-2:
1997, pp 1-29 3. U.S. Department of Health and Human Services: Recommendations for prophylaxis
against Pneumocystis carinii pneumonia for adults and adolescents infected with human
immunodeficiency virus. MMWR Morb Mortal Wkly Rep 43 no. RR-3: 1994, pp 1-21
T- and B-Cell Quantitation and Lymphocyte Proliferation to
Antigens and Mitogens Panel
Clinical Information: See individual test IDs.
Useful For: Assessing antigen-specific T-cell responses, global T-cell function, and quantitating
lymphocyte subsets in a single orderable test. This panel is most helpful when evaluating patients with
immunodeficiencies, where quantitative decreases in T cells can lead to reduced functional antigen and/or
mitogen responses. See individual test IDs for additional information.
Interpretation: Since the presence of lymphopenia, particularly in the T-cell compartment, can reduce
the magnitude of the proliferative response to both mitogens and antigens, it is helpful to perform
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