Sorted By Test Name - Mayo Medical Laboratories

LAA
8665
FLACT
91560
FLDYB
91668
Clinical References: Tietz Textbook of Clinical Chemistry. Edited by CA Burtis, ER Ashwood.
Philadelphia, WB Saunders Company, 2001
Lactate, Plasma
Clinical Information: Lactate is the end product of anaerobic carbohydrate metabolism. Major sites
of production are skeletal muscle, brain, and erythrocytes. Lactate is metabolized by the liver. The
concentration of lactate depends on the rate of production and the rate of liver clearance. The liver can
adequately clear lactate until the concentration reaches approximately 2 mmol/L. When this level is
exceeded, lactate begins to accumulate rapidly. For example, while resting lactate levels are usually 20 mmol/L within a few seconds. Lactic acidosis
signals the deterioration of the cellular oxidative process and is associated with hyperpnea, weakness,
fatigue, stupor, and finally coma. These conditions may be irreversible, even after treatment is
administered. Lactate acidosis may be associated with hypoxic conditions (eg, shock, hypovolemia, heart
failure, pulmonary insufficiency), metabolic disorders (eg, diabetic ketoacidosis, malignancies), and toxin
exposures (eg, ethanol, methanol, salicylates).
Useful For: Diagnosing and monitoring patients with lactic acidosis
Interpretation: While no definitive concentration of lactate has been established for the diagnosis of
lactic acidosis, lactate concentrations exceeding 5 mmol/L and pH 2 years: 0.6-2.3 mmol/L
Clinical References: 1. Mizock BA: The hepatosplanchnic area and hyperlactatemia: A tale of two
lactates. Crit Care Med 2001;29(2):447-449 2. Duke T: Dysoxia and lactate. Arch Dis Child
1999;81(4):343-350
Lactoferrin Detection
Reference Values:
Negative
Human lactoferrin is secreted by most mucosal membranes and is a major component of
polymorphonuclear leukocytes during an inflammatory response. During intestinal inflammation,
leukocytes migrate to the mucosa and infiltrate the intestinal lumen, increasing the level of fecal
lactoferrin. Inflammatory bowel disease (IBD) is comprised of ulcerative colitis and Crohnâ€s
disease, both of which are highly inflammatory and are diagnosed by ruling out infectious agents and
other potential causes of inflammation. This test for the qualitative detection of elevated levels of fecal
lactoferrin can help to identify patients with active IBD and rule out those with active irritable bowel
syndrome, which does not involve intestinal inflammation. This test can also be used as an indicator of
inflammatory diarrhea caused by the presence of a bacterial pathogen. A positive test result indicates that
the specimen contains elevated levels of lactoferrin.
Test Performed By:
Focus Diagnostics, Inc.
5785 Corporate Ave.
Cypress, CA 90630-4714
Ladybeetle Asian IgE
Interpretation: Conventional RAST Scoring Guide Class IgE (kU/L Comment 0