Sorted By Test Name - Mayo Medical Laboratories

9881
60694
Reporting limit determined each analysis
Creatinine (mg/L)
U.S. Population (10th – 90th percentiles, median)
All participants:
335 - 2370 mg/L, median: 1180 (n=22,245)
Males:
495 - 2540 mg/L, median: 1370 (n=10,610)
Females:
273 - 2170 mg/L, median 994 (n=11,635)
Formic Acid (mcg/mL)
Synonym(s): Formate
Normal 95% population range: 5-36 mcg/mL urine.
Formic Acid (Creatinine Corrected) (mg/g Creat)
Synonym(s): Formate
Specific Gravity Confirmation
Physiologic range: 1.010-1.030.
Test Performed By: NMS Labs
3701 Welsh Road
PO Box 433A
Willow Grove, PA 19090-0437
Fouchet's Stain for Bile
Useful For: Histologic method for demonstration of bile pigments.
Reference Values:
The laboratory will provide a pathology consultation and stained slide.
FOXL2 Mutation (C402G) Analysis by PCR and Pyrosequencing
Clinical Information: Granulosa cell tumor (GCT) represents approximately 5% to 10% of all
ovarian malignancies and is the most common type of malignant ovarian sex-cord stromal tumor. The
majority of patients with GCT (95%) are adults and 5% are juveniles. The histopathological diagnosis of
GCT is challenging. Forkhead box L2 (FOXL2) gene is involved in ovarian development and function.
The FOXL2 gene point mutation 402C->G in exon 1 (C134W) was reported in the majority of adult GCT
(>90%), 5% to 10% of thecomas (tumors closely related to GCT) and G supports the diagnosis
of granulosa cell tumor (GCT), but does not rule-out the diagnosis of ovarian thecomas (5%-10%). The
presence of wild-type FOXL2 does not rule-out the diagnosis of GCT.
Reference Values:
Negative
Clinical References: 1. Shah SP, Kobel M, Senz J, et al: Mutation of FOXL2 in granulosa-cell
tumors of the ovary. N Engl J Med 2009;360:2719-2729 2. Kim MS, Hur SY, Yoo NJ, et al: Mutational
analysis of FOXL2 codon 134 in granulosa cell tumour of ovary and other human cancers. J Pathol
2010;221:147-152 3. Schrader KA, Gorbatcheva B, Senz J, et al: The specificity of the FOXL2
Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 768