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PHBF<br />

8029<br />

RPOU<br />

84007<br />

POU<br />

8526<br />

West J Med 1987;147: 569-576<br />

Phosphorus, Body Fluid<br />

Clinical Information: Not available<br />

Useful For: Not established<br />

Interpretation: None available<br />

Reference Values:<br />

Not Applicable<br />

Clinical References: Tietz Textbook of Clinical Chemistry. Edited by Burtis and Ashwood.<br />

Philadelphia, WB Saunders Co, 1994<br />

Phosphorus, Pediatric, Random, Urine<br />

Clinical Information: Approximately 80% of filter phosphorous is reabsorbed by renal proximal<br />

tubule cells. The regulation of urinary phosphorous excretion is principally dependent on regulation of<br />

proximal tubule phosphorous reabsorption. A variety of factors influence renal tubular phosphate<br />

reabsorption, and consequent urine excretion. Factors that increase urinary phosphorous excretion include<br />

high phosphorous diet, parathyroid hormone, extracellular volume expansion, low dietary potassium<br />

intake and proximal tubule defects (eg, Fanconi syndrome, X-linked hypophosphatemic rickets,<br />

tumor-induced osteomalacia). Factors that decrease, or are associated with decreases in, urinary<br />

phosphorous excretion include low dietary phosphorous intake, insulin, high dietary potassium intake, and<br />

decreased intestinal absorption of phosphorous (eg, phosphate-binding antacids, vitamin D deficiency,<br />

malabsorption states). A renal leak of phosphate has also been implicated as contributing to kidney stone<br />

formation in some patients.<br />

Useful For: Evaluation of hypo- or hyperphosphatemic states Evaluation of patients with<br />

nephrolithiasis A timed 24-hour urine collection is the preferred specimen for measuring and interpreting<br />

this urinary analyte. Random collections normalized to urinary creatinine may be of some clinical use in<br />

patients who cannot collect a 24-hour specimen, typically small children. Therefore, this random test is<br />

offered for children 0.34 0.34 0.34 0.33 0.33 0.32<br />

0.22 0.21

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