07.01.2013 Views

Sorted By Test Name - Mayo Medical Laboratories

Sorted By Test Name - Mayo Medical Laboratories

Sorted By Test Name - Mayo Medical Laboratories

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

CLIPG<br />

87987<br />

Interpretation: Positive and strongly positive results for phospholipid antibodies (> or =40 GPL<br />

and/or MPL) are a diagnostic criterion for antiphospholipid syndrome (APS). Lesser levels of<br />

phospholipid antibodies and antibodies of the IgA isotype may occur in patients with clinical signs of<br />

APS but the results are not considered diagnostic. Detection of phospholipid antibodies is not affected by<br />

anticoagulant treatment.<br />

Reference Values:<br />

or =80.0 MPL or GPL (strongly positive)<br />

MPL refers to IgM Phospholipid Units. One MPL unit is 1 microgram of IgM antibody.<br />

GPL refers to IgG Phospholipid Units. One GPL unit is 1 microgram of IgG antibody.<br />

Reference values apply to all ages.<br />

Clinical References: 1. Bevers EM, Comfurius P, Dekkers DW, et al: Lipid translocation across the<br />

plasma membrane of mammalian cells. Biochim Biophys Acta 1999;1439:317-330 2. Arnout J, Vermylen<br />

J: Current status and implications of autoimmune antiphospholipid antibodies in relation to thrombotic<br />

disease. J Thromb Haemost 2003;1:931-942 3. Proven A, Bartlett RP, Moder KG, et al: Clinical<br />

importance of positive test results for lupus anticoagulant and anticardiolipin antibodies. <strong>Mayo</strong> Clin Proc<br />

2004;79:467-475 4. Wilson WW, Gharavi AE, Koike T, et al: International consensus statement on<br />

preliminary classification criteria for definite antiphospholipid syndrome. Arthritis Rheum<br />

1999;42(7):1309-1311 5. Fontaine MJ, Jacob GL, Nichols WL, et al: Comparative evaluation of three<br />

assays for anti-cardiolipin antibodies. J Autoimmun 2000;15(2):A56 6. Favaloro EJ, Wong RC, Silvertrini<br />

R, et al: A multilaboratory peer assessment quality assurance program-based evaluation of anticardiolipin<br />

antibody, and beta 2 glycoprotein 1 antibody testing. Semin Thromb Hemost 2005;31(1):73-84<br />

Phospholipid (Cardiolipin) Antibodies, IgG, IgM, and IgA, Serum<br />

Clinical Information: See Individual Unit Codes<br />

Useful For: See Individual Unit Codes<br />

Interpretation: See Individual Unit Codes<br />

Reference Values:<br />

PHOSPHOLIPID ANTIBODIES, IgG<br />

or =80.0 GPL (strongly positive)<br />

GPL refers to IgG Phospholipid Units. One GPL unit is 1 microgram of IgG antibody.<br />

Reference values apply to all ages.<br />

PHOSPHOLIPID ANTIBODIES, IgM<br />

or =80.0 MPL (strongly positive)<br />

MPL refers to IgM Phospholipid Units. One MPL unit is 1 microgram of IgM antibody.<br />

Reference values apply to all ages.<br />

PHOSPHOLIPID ANTIBODIES, IgA<br />

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!