Sorted By Test Name - Mayo Medical Laboratories

FMYOP
91545
FMY3P
57279
in various conditions including some metabolic diseases. Conditions associated with myoglobinuria
include: -Hereditary myoglobinuria -Phosphorylase deficiency -Sporadic myoglobinuria -Exertional
myoglobinuria in untrained individuals -Crush syndrome -Myocardial infarction -Myoglobinuria of
progressive muscle disease -Heat injury(1,2) Urine myoglobin increases with muscle necrosis, but the
clinical consequences are variable. Therefore, myoglobin can confirm a clinical diagnosis of myopathy,
but an elevated urine excretion of myoglobin is not specific for a clinical disorder.(1,2) In acute renal
failure, an elevated urinary myoglobin can suggest a potential cause and, consequently, may indicate
appropriate treatment courses. Urine myoglobin cross-reacts with standard urine dipstick tests for
hemoglobin (false-positive). If the dipstick is positive for hemoglobin but the urine contains no or few
RBCs, the urine myoglobin test may help confirm or rule out hemoglobinuria.
Useful For: Confirming the presence of a myopathy associated with any 1 of the above disorders May
suggest a myopathic cause for acute renal failure Follow-up testing for specimens with positive urine
hemoglobin results by the dipstick method
Interpretation: Increased excretion of urinary myoglobin suggests the disorders listed above. Most
clinically significant elevations are elevated 2 to 10 times normal. Visual pigmenturia occurs at
myoglobin concentrations is about 160 times normal (approximately 4 mcg/mL). Renal toxicity depends
on multiple factors such as renal perfusion and degree of acidity of urine.
Reference Values: