Sorted By Test Name - Mayo Medical Laboratories

TGLBF
61647
TRIG
8316
DOXEPIN AND NORDOXEPIN
Therapeutic concentration: 50-150 ng/mL
Toxic concentration: > or =300 ng/mL
Clinical References: 1. Wille SM, Cooreman SG, Neels HM, Lambert WE: Relevant issues in the
monitoring and the toxicology of antidepressants. Crit Rev Clin Lab Sci 2008;45(1):25-89 2. Thanacoody
HK, Thomas SH: Antidepressant poisoning. Clin Med 2003;3(2):114-118 3. Baumann P, Hiemke C,
Ulrich S, et al: The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in
psychiatry. Pharmacopsychiatry 2004;37(6):243-265
Triglycerides, Body Fluid
Clinical Information: The presence of a chylous effusion, which results from lymphatic drainage
into a body cavity, can be determined by identifying triglycerides and chylomicrons in the fluid.
Catheter-related iatrogenic effusions can be identified by determining the presence of intravenous solution
constituents in the fluid.
Useful For: Distinguishing between chylous and nonchylous effusions Determining if bleeding has
occurred in a body fluid Identifying iatrogenic effusions
Interpretation: Triglyceride concentration >110 mg/dL is highly suggestive of a chylous effusion.
Reference Values:
Not applicable
Clinical References: Ellefson RD, Elveback L, Weidman W: Plasma lipoproteins of children and
youths in Rochester, MN. DHEW Publication No. (NIH) 1978;78-1472
Triglycerides, Serum
Clinical Information: Triglycerides are esters of the trihydric alcohol glycerol with 3 long-chain fatty
acids. They are partly synthesized in the liver and partly derived from the diet. Increased plasma
triglyceride levels are indicative of a metabolic abnormality and, along with elevated cholesterol, are
considered a risk factor for atherosclerotic disease. Hyperlipidemia may be inherited or be associated with
biliary obstruction, diabetes mellitus, nephrotic syndrome, renal failure, or metabolic disorders related to
endocrinopathies. Increased triglycerides may also be medication-induced (eg, prednisone).
Useful For: Evaluation of risk factors in individuals with elevated cholesterol values. Since cholesterol
and triglycerides can vary independently, measurement of both is more meaningful than the measurement
of cholesterol only.
Interpretation: In the presence of other coronary heart disease risk factors, both borderline high
(150-199 mg/dL) and high values (>200 mg/dL) require attention. Triglyceride concentrations >1,000
mg/dL can lead to abdominal pain and may be life-threatening due to chylomicron-induced pancreatitis.
Also see Lipids and Lipoproteins in Blood Plasma (Serum) in Special Instructions.
Reference Values:
The National Cholesterol Education Program (NCEP) has set the following guidelines for lipids (total
cholesterol, triglycerides, HDL, and LDL cholesterol) in adults ages 18 and up:
TRIGLYCERIDES
Normal: or =500 mg/dL
The National Cholesterol Education Program (NCEP) and National Health and Nutrition Examination
Survey (NHANES) has set the following guidelines for lipids (total cholesterol, triglycerides, HDL, and
LDL cholesterol) in children ages 2 to 17:
Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 1790