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Sorted By Test Name - Mayo Medical Laboratories

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FBENZ<br />

90092<br />

-Lorazepam -Hydroxyethylfluorazepam (metabolite of flurazepam) -Alpha hydroxyalprazolam<br />

(metabolite of alprazolam) -Alpha hydroxytriazolam (metabolite of triazolam) -7-aminoclonazepam<br />

(metabolite of clonazepam) -7-aminoflunitrazepam (metabolite of flunitrazepam) The clearance half-life<br />

of long-acting benzodiazepines is >24 hours. It takes 5 to 7 half-lives to clear 98% of a drug dose.<br />

Therefore, the presence of a long-acting benzodiazepine greater than the limit of quantification indicates<br />

exposure within a 5-day to 20-day interval preceding specimen collection. Following a dose of diazepam,<br />

the drug and its metabolites appear in the urine within 30 minutes. Peak urine output is reached between 1<br />

and 8 hours. See <strong>Mayo</strong> <strong>Medical</strong> <strong>Laboratories</strong> Drugs of Abuse <strong>Test</strong>ing Guide at<br />

http://www.mayomedicallaboratories.com/articles/drug-book/print-on-demand-select.php for additional<br />

information including metabolism, clearance (half-life), and approximate detection times.<br />

Reference Values:<br />

Negative<br />

Positives are reported with a quantitative GC-MS result.<br />

Cutoff concentrations:<br />

IMMUNOASSAY SCREEN<br />

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