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12-23 months: 2,100-6,200 cells/mcL*<br />

2-5 years: 1,400-3,700 cells/mcL*<br />

6-11 years: 1,200-2,600 cells/mcL*<br />

12-17 years: 1,000-2,200 cells/mcL*<br />

> or =18 years: 582-1,992 cells/mcL<br />

Helper Cells (CD4)<br />

0-2 months: 1,600-4,000 cells/mcL*<br />

3-5 months: 1,800-4,000 cells/mcL*<br />

6-11 months: 1,400-4,300 cells/mcL*<br />

12-23 months: 1,300-3,400 cells/mcL*<br />

2-5 years: 700-2,200 cells/mcL*<br />

6-11 years: 650-1,500 cells/mcL*<br />

12-17 years: 530-1,300 cells/mcL*<br />

> or =18 years: 401-1,532 cells/mcL<br />

Suppressor Cells (CD8)<br />

0-2 months: 560-1,700 cells/mcL*<br />

3-5 months: 590-1,600 cells/mcL*<br />

6-11 months: 500-1,700 cells/mcL*<br />

12-23 months: 620-2,000 cells/mcL*<br />

2-5 years: 490-1,300 cells/mcL*<br />

6-11 years: 370-1,100 cells/mcL*<br />

12-17 years: 330-920 cells/mcL*<br />

> or =18 years: 152-838 cells/mcL<br />

*Shearer WT, Rosenblatt HM, Gelman RS, et al: Lymphocyte subsets in healthy children from birth<br />

through 18 years of age: The Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol<br />

2003;112(5):973-980<br />

TREC, Immune Reconstitution<br />

Pediatric<br />

0-2 months: not established<br />

6 months-18 years: >801 copies per million peripheral blood mononuclear cells<br />

Adults<br />

19-44 years: >227 copies per million CD3 T cells<br />

45-54 years: >111 copies per million CD3 T cells<br />

> or =55 years: >78 copies per million CD3 T cells<br />

TREC results are expressed as copies per million CD3 T cells for adult specimens or per million<br />

peripheral blood mononuclear cells for pediatric specimens.<br />

CD4 T-CELL RECENT TYMIC EMIGRANTS (RTE)<br />

CD4 Absolute<br />

Males<br />

1 month-17 years: 153-1,745 cells/mcL<br />

18-70 years: 290-1,175 cells/mcL<br />

Females<br />

1 month-17 years: 582-1,630 cells/mcL<br />

18-70 years: 457-1,766 cells/mcL<br />

Reference values have not been established for patients that are 70 years of age.<br />

CD4 RTE %<br />

Males<br />

1 month-17 years: 19.4-60.9%<br />

18-25 years: 6.4-51.0%<br />

26-55 years: 6.4-41.7%<br />

56-70 years: 6.4-27.7%<br />

Females<br />

1 month-17 years: 25.8-68.0%<br />

18-25 years: 6.4-51.0%<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1740

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