Sorted By Test Name - Mayo Medical Laboratories

NITU
8586
NMDCS
61516
muscle protein to meet the metabolic requirements of the body and is, therefore, in a catabolic state.
Useful For: Assessing nutritional status (protein malnutrition), evaluating protein catabolism, and
determining nitrogen balance, when used in conjunction with 24-hour fecal nitrogen measurement.
Interpretation: Average fecal nitrogen excretion is approximately 2 g/day, but fecal nitrogen excretion
is highly variable, especially in conditions resulting in excessive protein catabolism. Significantly
abnormal excretion rates, resulting in negative nitrogen balance, may be associated with severe stress due
to multiple trauma, head injury, sepsis, or extensive burns. Elevated values >2.5 g total fecal nitrogen/24
hours are usually found in cases of chronic progressive pancreatitis. The goal with therapy for a depleted
person is a positive nitrogen balance of 4 g nitrogen/24 horus to 6 g nitrogen/24-hours.
Reference Values:
or =16 years: 1-2 g/24 hours
Clinical References: 1. Phinney SD: The assessment of protein nutrition in the hospitalized patient.
Clin in Lab Med 1981;1:767-774 2. Veldee MS. Nutritional assessment, therapy, and monitoring, In:
Tietz Textbook of Clinical Chemistry. 3rd edition. Edited by CA Burtis, ER Ashwood: Philadelphia, WB
Sanders Company, 1999; pp 1385-1386 3. Konstantinides FN, Kostantinides NN, Li JC, et al. Urinary
urea nitrogen: too insensitive for calculating nitrogen balance studies in surgical clinical nutrition. J
Parenter Enteral Nutr 1991;15:189-193
Nitrogen, Total, Urine
Clinical Information: Nitrogen is a key component of proteins. During protein catabolism
(proteolysis), nitrogen is excreted in the urine and feces. Protein catabolism may be increased after stress
(eg, physical trauma, surgery, infections, burns). "Nitrogen balance" is the difference between the amount
of nitrogen ingested and the amount excreted. A patient who is in negative nitrogen balance is using
muscle protein to meet the metabolic requirements of the body and is, therefore, in a catabolic state.
Useful For: Assessing nutritional status (protein malnutrition), evaluating protein catabolism, and
determining nitrogen balance, when used in conjunction with 24-hour fecal nitrogen measurement
Interpretation: Twenty-four hour urinary nitrogen excretion levels within the normal range are
indicative of adequate nutrition. Slightly abnormal excretion rates may be a result of moderate stress or
complications such as infection or trauma. Significantly abnormal excretion rates may be associated with
severe stress due to multiple trauma, head injury, sepsis, or extensive burns. The goal with therapy for a
depleted person is a positive nitrogen balance of 4 g nitrogen/24 hours to 6 g nitrogen/24 hours.
Reference Values:
or =16 years: 4-20 g/24 hours
Clinical References: 1. Phinney SD: The assessment of protein nutrition in the hospitalized patient.
Clin Lab Med 1981;1:767-774 2. Veldee MS: Nutritional assessment, therapy, and monitoring. In Tietz
Textbook of Clinical Chemistry. 3rd edition. Edited by CA Burtis, ER Ashwood. Philadelphia, WB
Saunders Company, 1999, pp 1385-1386 3. Konstantinides FN, Kostantinides NN, Li JC, et al: Urinary
urea nitrogen: too insensitive for calculating nitrogen balance studies in surgical clinical nutrition. J
Parenter Enteral Nutr 1991;15:189-193
NMDA-Receptor Antibody by CBA, Serum
Clinical Information: Patients with NMDA-receptor antibody (targeting the GluN1 [NR1] subunit of
this ionotropic glutamate receptor) have a fairly stereotyped neurological disorder, as described by
Dalmau and colleagues. This disorder often develops in several stages. Prodromal symptoms include
headache, fever, nausea, vomiting, diarrhea, or upper respiratory tract symptoms. Shortly afterwards,
patients develop psychiatric symptoms and many initially come to the attention of psychiatrists. Anxiety,
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