Sorted By Test Name - Mayo Medical Laboratories

FSED
91811
SEU
9793
bicarbonate secretion. Secretin also stimulates secretion of bile, release of Insulin, and release of Gastric
Pepsin in the stomach. Secretin inhibits Glucagon release, intestinal motility, and prevents the uptake of
water and sodium ions by the intestine. In normal patients, Secretin has little effect on Gastrin levels, but
stimulates Gastrin greatly in Zollinger-Ellison patients. Secretin is also elevated in Zollinger-Ellison
patients and in patients with duodenal ulcer. Secretin levels are low in patients with pernicious anemia and
achlorhydria. Secretin secretion can be suppressed by Somatostatin, Cimetidine, and
Methionine-Enkephalin.
Reference Values:
12-75 pg/mL (mean=25)
This test was developed and its performance characteristics determined by Inter Science Institute. It has
not been cleared or approved by the US Food and Drug Administration. The FDA has determined that
such clearance or approval is not necessary.
Test Performed by: Inter Science Institute
944 West Hyde Park
Inglewood, CA 90302
Sedative Hypnotic Panel, Urine-Forensic
Reference Values:
Ethyl Alcohol is screened by an enzymatic method; positive
results are confirmed by Gas Chromatography (GC).
Drugs are screened by Immunoassay; positive results are
confirmed by Gas Chromatography with Mass Spectrometry
(GC/MS). The following threshold concentrations are used
for this analysis.
Drug Screening Threshold Confirmation Threshold
Ethyl Alcohol 0.020 gm/dL 0.020 gm/dL
Barbiturates 300 ng/mL 100 ng/mL
Benzodiazepines 100 ng/mL 75 ng/mL
Flunitrazepam 100 ng/mL 300 ng/Ml
Ketamine
Gamma-Hydroxybutyric Acid (GHB): Negative
Test Performed By: Medtox Laboratories, Inc.
402 W. County Road D
St. Paul, MN 55112
Selenium, 24 Hour, Urine
Clinical Information: Selenium is an essential element. It is a cofactor required to maintain
glutathione peroxidase (GSH-Px) activity, an enzyme that catalyzes the degradation of organic
hydroperoxides. The absence of selenium correlates with loss of GSH-Px activity and is associated with
damage to cell membranes due to accumulation of free radicals. In humans, cardiac muscle is the most
susceptible to selenium deficiency. With cell membrane damage, normal cells are replaced by fibroblasts.
This condition is known as cardiomyopathy and is characterized by an enlarged heart whose muscle is
largely replaced by fibrous tissue. In the United States, deficiency is related to use of total parenteral
nutrition. This is therapy administered to patients with no functional bowel, such as after surgical removal
of the small and large intestine because of cancer, or because of acute inflammatory bowel disease such as
Crohn's disease. Selenium supplementation to raise serum concentration >90 ng/mL is the usual
treatment. Serum monitoring done on a semiannual basis checks the adequacy of supplementation.
Selenium toxicity has been observed in animals when daily intake exceeds 4 parts per million (ppm).
Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 1567