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PBHA<br />

8495<br />

PBNA<br />

89857<br />

standards for employees working in industry: -Employees with a single whole blood lead result >60<br />

mcg/dL must be removed from workplace exposure. -Employees with whole blood lead levels >50<br />

mcg/dL averaged over 3 blood samplings must be removed from workplace exposure. -An employee may<br />

not return to work in a lead exposure environment until their whole blood lead level is or =7 years: 0-9 mcg/dL<br />

Critical values<br />

Pediatrics (< or =15 years): > or =20 mcg/dL<br />

Adults (> or =16 years): > or =70 mcg/dL<br />

Clinical References: 1. Occupational Safety and Health Administration: OSHA Lead Standard -<br />

Requirements from the General Industry Standards Lead (1910.1025), from 29 CFR 1910.1025, A.M.<br />

Best Safety and Security - 2000. Cited March 2000. Available from URL:<br />

http://www.ambest.com/safety/osha/chap10g.html 2. Rosen JF: Preventing Lead Poisoning in Young<br />

Children. US Public Health Service, Centers for Disease Control, Atlanta, GA, 1991 3. Bellinger D,<br />

Leviton A, Waternaux C, et al: Longitudinal analyses of prenatal and postnatal lead exposure and early<br />

cognitive development. N Engl J Med 1987 Apr 23;316(17):1037-1043 4. Needleman HL, Schell A,<br />

Bellinger D, et al: The long-term effects of exposure to low doses of lead in childhood. An 11-year<br />

follow-up report. N Engl J Med 1990 Jan 11;322(2):83-88 5. Nixon DE, Moyer TP, Windebank AJ, et al:<br />

Lack of correlation of low level sof whole blood and serum lead in humans: an experimental evaluation in<br />

animals. In Trace Substances in Envrionmental Health XIX. Proceedings of the University of Missouri's<br />

19th Annual Conference on Trace Substances in Environmental Health, Columbia, MO, June 3-6, 1985,<br />

pp248-256<br />

Lead, Hair<br />

Clinical Information: Hair analysis for lead can be used to corroborate blood analysis or to document<br />

past lead exposure. If the hair is collected and segmented in a time sequence (based on length from root),<br />

the approximate time of exposure can be assessed.<br />

Useful For: Detecting lead exposure<br />

Interpretation: Normal hair lead content is 10.0 mcg/g indicates significant<br />

lead exposure.<br />

Reference Values:<br />

0.0-3.9 mcg/g of hair<br />

Reference values apply to all ages.<br />

Clinical References: 1. Strumylaite L, Ryselis S, Kregzdyte R: Content of lead in human hair from<br />

people exposed to lead. Int J Hyg Environ Health 2004;207:345-351 2. Barbosa F, Tanus-Santos J,<br />

Gerlach R, and Parsons P: A Critical review of biomarkers used for monitoring human exposure to lead:<br />

advantages, limitations, and future needs. Environ Health Perspect 2005;113:1669–1674 3. Sanna E,<br />

Liguori A, Palmes L, et al: Blood and hair lead levels in boys and girls living in two Sardinian towns at<br />

different risks of lead pollution. Ecotoxicol Environ Saf 2003;55:293-299<br />

Lead, Nails<br />

Clinical Information: Nail analysis of lead can be used to corroborate blood analysis.<br />

Useful For: Detecting lead exposure<br />

Interpretation: Normally, the nail lead content is 10.0 mcg/g indicates<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1094

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