Sorted By Test Name - Mayo Medical Laboratories

F5M
57101
6MAMM
89659
Useful For: Biochemical diagnosis and monitoring of intestinal carcinoid syndrome
Interpretation: Elevated excretion of 5-hydroxyindoleacetic acid is a probable indicator of the
presence of a serotonin-producing tumor, if pharmacological and dietary artifacts have been ruled out.
Reference Values:
Adults: < or =8 mg/24 hours
Clinical References: 1. de Herder W: Biochemistry of neuroendocrine tumours. Best Pract Res Clin
Endocrinol Metab 2007 Mar;21(1):33-41 2. Manini P, Andreoli R, Cavazzini S, et al: Liquid
chromatography-electrospray tandem mass spectrometry of acidic monoamine metabolites. J Chromatogr
B Biomed Sci Appl 2000 July 21;744(2):423-431 3. Mashige F, Matsushima Y, Kanazawa H, et al:
Acidic catecholamine metabolites and 5-hydroxyindoleacetic acid in urine: the influence of diet. Ann Clin
Biochem 1996;33:43-49 4. Mills K: Serotonin syndrome - A clinical update. Crit Care Clin
1997;13:763-783 5. Serotonin syndrome. In POISINDEX System. Edited by RK Klasco, CR Gelman, LT
Hill. Greenwood Village, Colorado, Micromedex, 2002
5-Methyltetrahydrofolate
Reference Values:
5-Methyltetrahydrofolate
Age 5MTHF
(years) (nmol/L)
0-0.2 40-240
0.2-0.5 40-240
0.5-2.0 40-187
2.0-5.0 40-150
5.0-10 40-128
10-15 40-120
Adults 40-120
Note: If test results are inconsistent with the clinical
presentation, please call our laboratory to discuss the case
and/or submit a second sample for confirmatory testing.
DISCLAIMER required by the FDA for high complexity clinical
laboratories: HPLC testing was developed and its performance
characteristics determined by Medical Neurogenetics. These
HPLC tests have not been cleared or approved by the U.S. FDA.
Test Performed By: Medical Neurogenetics Lab
5424 Glenridge Drive NE
Atlanta, GA 30342
6-Monoacetylmorphine (6-MAM), Confirmation, Meconium
Clinical Information: Heroin (diacetylmorphine) is a semisynthetic opiate that is closely related to
morphine. It is no longer used clinically in the United States, though it is used everywhere for rapid relief
of pain.(1) Like morphine and other opiates, its relaxing and euphoric qualities make heroin a popular
drug of abuse. Heroin is commonly injected intravenously, although it can be administered by other
means such as snorting, smoking, or inhaling vapors. Heroin shares the core structure of morphine, with
the addition of 2 acetyl groups, which are thought to enhance its permeation into the central nervous
system.(2,3) Heroin is metabolized by sequential removal of these acetyl groups; loss of the first acetyl
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