Sorted By Test Name - Mayo Medical Laboratories

FBOMB
90174
BAP
82985
and to define the allergens responsible for eliciting signs and symptoms. Testing also may be useful to
identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm
sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of
allergic reactions to insect venom allergens, drugs, or chemical allergens.
Interpretation: Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased
likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be
responsible for eliciting signs and symptoms. The level of IgE antibodies in serum varies directly with the
concentration of IgE antibodies expressed as a class score or kU/L.
Reference Values:
Class IgE kU/L Interpretation
0 Negative
1 0.35-0.69 Equivocal
2 0.70-3.49 Positive
3 3.50-17.4 Positive
4 17.5-49.9 Strongly positive
5 50.0-99.9 Strongly positive
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by
Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders
Company, 2007, Chapter 53, Part VI, pp 961-971
Bombesin
Clinical Information: Bombesin is a 14 amino acid peptide with strong Gastrin and gastric acid
releasing properties. Bombesin also increases pancreatic enzyme output. Bombesin is found in high
concentrations in the lung and has been proposed as a marker for oat-cell carcinoma. Bombesin
hypersecretion has been associated with several physiological effects including anorexia, hypothermia,
and hyperglycemia. It is also increased in small lung cell carcinoma and tumors of the APUD series.
Bombesin infusion increases Neurotensin, Gastric Inhibitory Polypeptide and Enteroglucagon levels, but
has no effect on pancreatic Glucagon.
Reference Values:
50-250 pg/mL
This test was developed and its performance characteristics determined by Inter Science Institute. It has
not been cleared or approved by the US Food and Drug Administration. The FDA has determined that
such clearance or approval is not necessary.
Test Performed by: Inter Science Inst
944 West Hyde Park
Inglewood, CA 90302
Bone Alkaline Phosphatase, Serum
Clinical Information: Bone alkaline phosphatase (BAP) is the bone-specific isoform of alkaline
phosphatase. A glycoprotein that is found on the surface of osteoblasts, BAP reflects the biosynthetic
activity of these bone-forming cells. BAP has been shown to be a sensitive and reliable indicator of bone
metabolism.(1) Normal bone is constantly undergoing remodeling in which bone degradation or
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