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UREDF<br />

83255<br />

4986<br />

1 0.35-0.69 Equivocal<br />

2 0.70-3.49 Positive<br />

3 3.50-17.4 Positive<br />

4 17.5-49.9 Strongly positive<br />

5 50.0-99.9 Strongly positive<br />

6 > or =100 Strongly positive Reference values<br />

apply to all ages.<br />

Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by<br />

Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders<br />

Company, 2007, Chapter 53, Part VI, pp 961-971<br />

Reducing Substance, Feces<br />

Clinical Information: Sugars (eg, glucose, galactose, fructose, maltose, lactose, and pentose) are<br />

characterized as reducing substances based on their ability to reduce cupric ions to cuprous ions. Fecal<br />

reducing substances may be increased in carbohydrate malabsorption syndromes.<br />

Useful For: Diagnosing intestinal malabsorption in children Assisting in the differentiation between<br />

osmotic and nonosmotic diarrhea Screening test for: -Diarrhea from disaccharidase deficiencies, (eg,<br />

lactase deficiency) -Monosaccharide malabsorption<br />

Interpretation: Negative: negative Normal: 0.50 g/dL (grade 2-4)<br />

Reference Values:<br />

Negative or trace<br />

Clinical References: Todd S: Archives of disease in childhood: differentiation of osmotic and<br />

secretory diarrhea by stool carbohydrate and osmolar measurements. In Clinical Diagnosis and<br />

Management by Laboratory Methods. Vol 77. 20th edition. Edited by JB Henry, FR Davey, CJ Herman,<br />

et al. Philadelphia, Saunders, 2001, pp 201-205<br />

Renal Biopsy, Electron Microscopy<br />

Clinical Information: Kidney biopsy has proven of value in the clinical evaluation and management<br />

of patients with undiagnosed kidney disease. The clinical setting may include acute renal failure,<br />

nephrotic syndrome, asymptomatic proteinuria and hematuria. Kidney diseases in the setting of a systemic<br />

disease are often diagnosed on kidney biopsy. Biopsy of the transplanted kidney is important in the<br />

determination of the presence of acute rejection, infection, or recurrent disease. Optimal interpretaion of a<br />

kidney biopsy requires integration of clinical and laboratory results with light microscopic,<br />

immunofluorescent histology, and electron microscopy findings. Electron microscopy is required for the<br />

diagosis of Alport syndrome, dense deposit disease, thin glomeular basement membrane nephropathy, and<br />

fibrillary glomerulonephritis; and is helpful in evaluating secondary causes of glomerulonephritis such as<br />

lupus nephritis.<br />

Useful For: Evaluation of patients with undiagnosed kidney disease Following the course of therapy or<br />

progression of disease Diagnosing disease with only electron microscopic alterations<br />

Interpretation: A written report is issued along with appropriate annotated electron microscopic<br />

photomicrographs.<br />

Reference Values:<br />

An interpretive report will be provided.<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1532

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