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CTBBL<br />

82443<br />

FMC12<br />

91558<br />

Useful For: Rapid detection of mycobacteria<br />

Interpretation: A final negative report is issued after 60 days incubation. Positive cultures are reported<br />

as soon as detected.<br />

Reference Values:<br />

Negative<br />

Clinical References: 1. Bloom BR, Murrary CJ: Tuberculosis: commentary on a reemergent killer.<br />

Science 1992;257:1055-1064 2. Horsburgh CR, Jr: Mycobacteruim avium complex infection in the<br />

acquired immunodeficiency syndrome. N Engl J Med 1991;423:1332-1338 3. Tenover FC, Crawford JT,<br />

Huebner RE, et al: The resurgence of tuberculosis: is your laboratory ready? J Clin Microbiol<br />

1993;31:767-770 4. Cohn ML, Waggoner RF, McClatchy JK: The 7H11 medium for the cultivation of<br />

mycobacteria. Am Rev Resp Dis 1968;98:295-296 5. Youmans GP: Cultivation of mycobacteria, the<br />

morphology and metabolism of mycobacteria. In Tuberculosis. Edited by GP Youmans, Philadelphia, WB<br />

Saunders Company, 1979, pp 25-35 6. Kent PT, Kubica GP: Public health mycobacteriology: a guide for<br />

the level III laboratory. USDHHS, Centers for Disease Control, Atlanta, GA, 1985<br />

Mycobacterial Culture, Blood<br />

Clinical Information: Mycobacteremia occurs most often in immunocompromised hosts. The<br />

majority of disseminated mycobacterial infections are due to Mycobacterium avium complex but<br />

bacteremia can also be caused by other mycobacterial species including, but not limited to,<br />

Mycobacterium tuberculosis complex, Mycobacterium kansasii, Mycobacterium fortuitum,<br />

Mycobacterium chelonae, Mycobacterium scrofulaceum, Mycobacterium szulgai, and Mycobacterium<br />

xenopi.(1) Mycobacterial blood cultures may be indicated for patients presenting with signs and<br />

symptoms of sepsis, especially fever of unknown origin.<br />

Useful For: Diagnosing mycobacteremia<br />

Interpretation: A positive result may support the diagnosis of mycobacteremia.<br />

Reference Values:<br />

Negative<br />

If positive, mycobacteria is identified.<br />

A final negative report will be issued after 60 days of incubation.<br />

Clinical References: 1. Pfyffer GE:Mycobacterium:General characteristics, laboratory detection,<br />

and staining procedures. In Manual of Clinical Microbiology. 9th edition. Edited by PR Murray, EJ<br />

Baron, JH Jorgensen, et al. ASM Press, Washington DC, 2007, pp 543-572 2. Reimer LG. Laboratory<br />

detection of mycobacteremia. Clin Lab Med 1994;14:99-105<br />

Mycobacterium MIC 12 Drug and Combination<br />

Reference Values:<br />

mcg/mL<br />

Includes:<br />

Ciprofloxacin MIC<br />

Clofazimine MIC<br />

Rifabutin MIC<br />

Rifampin MIC<br />

Kanamycin MIC<br />

Cycloserine MIC<br />

Ethionamide MIC<br />

Ethambutol MIC<br />

Streptomycin MIC<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1264

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