Sorted By Test Name - Mayo Medical Laboratories

FPNTS
57311
PGSN
8141
Procollagen Type I Intact N-Terminal Propeptide
Reference Values:
Males: 22-105 ug/L
Females:
Premenopausal: 20-101 ug/L
Postmenopausal: 16-96 ug/L
Test Performed by: ARUP Laboratories, Inc.
500 Chipeta Way
Salt Lake City, UT 84108
Progesterone, Serum
Clinical Information: Sources of progesterone are the adrenal glands, corpus luteum, and placenta:
Adrenal Glands Progesterone synthesized in the adrenal glands is converted to other corticosteroids and
androgens and, thus, is not a major contributor to circulating serum levels unless there is a
progesterone-producing tumor present. Corpus Luteum After ovulation, there is a significant rise in serum
levels as the corpus luteum begins to produce progesterone in increasing amounts. This causes changes in
the uterus, preparing it for implantation of a fertilized egg. If implantation occurs, the trophoblast begins
to secrete human chorionic gonadotropin, which aintains the corpus luteum and its secretion of
progesterone. If there is no implantation, the corpus luteum degenerates and circulating progesterone
levels decrease rapidly, reaching follicular phase levels about 4 days before the next menstrual period.
Placenta By the end of the first trimester, the placenta becomes the primary secretor of progesterone.
Useful For: Ascertaining whether ovulation occurred in a menstrual cycle Evaluation of placental
function in pregnancy Workup of some patients with adrenal or testicular tumors
Interpretation: Ovulation results in a mid-cycle surge of luteinizing hormone (LH) followed by an
increase in progesterone secretion, with a peak being reached between day 21 and 23. If no fertilization
and implantation has occurred by then, supplying the corpus luteum with human chorionic
gonadotropin-driven growth stimulus, progesterone secretion falls, ultimately triggering menstruation. A
day 21 to 23 serum progesterone peak of 6.5 ng/mL to 7 ng/mL is the minimal level considered consistent
with ovulation. A level in excess of 18 ng/mL is considered conclusive proof of ovulation. Placental
insufficiency has been associated with low levels of LH and progesterone. Levels of LH and progesterone
may be increased in some adrenal or testicular tumors.
Reference Values:
Males
Cord blood: 569-1,107 ng/mL*
0-23 months: 0.87-3.37 ng/mL*
2-9 years: or =18 years: 0.20-1.40 ng/mL
Females
Cord blood: 569-1,107 ng/mL*
0-23 months: 0.87-3.37 ng/mL*
2-9 years: 0.20-0.24 ng/mL*
10-17 years: values increase through puberty and adolescence.*
Premenopausal
Follicular phase: 0.20-1.50 ng/mL
Ovulation phase: 0.80-3.00 ng/mL
Luteal phase: 1.70-27.00 ng/mL
Postmenopausal: