Sorted By Test Name - Mayo Medical Laboratories

9828
MCC
88636
9230
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by
Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders
Company, 2007, Chapter 53, Part VI, pp 961-971
Masson's Trichrome Stain for Connective Tissue
Useful For: Method for collagen and cardiac or skeletal muscle fibers.
Reference Values:
The laboratory will provide a pathology consultation and stained slide.
Maternal Cell Contamination, Molecular Analysis
Clinical Information: One of the risks associated with prenatal testing is maternal cell contamination
(MCC), which can occur when a fetal specimen comes into contact with maternal blood or tissue. The risk
of MCC is associated with procedures such as chorionic villus sampling, amniocentesis, or extraction of
fetal blood from the umbilical cord (cord blood). If MCC is present, the maternal DNA may mask the
results of any genetic testing performed on the fetal DNA. Therefore, the results of prenatal testing may
be compromised. To rule out the presence of MCC, a maternal blood specimen is necessary for
comparison of maternal and fetal chromosomal markers. The presence of both maternal and non-maternal
alleles for each fetal marker indicates the fetal specimen is not contaminated. MCC is confirmed when
both alleles in the fetus are maternal.
Useful For: Ruling out the presence of maternal cell contamination within a fetal specimen This test is
required for all prenatal testing performed in Mayo's molecular and biochemical genetics laboratories
Interpretation: An interpretive report will be provided.
Reference Values:
An interpretative report will be provided.
Maturation Smear
Clinical Information: Maturation of the vaginal squamous epithelium is hormone dependent;
estrogen stimulates proliferation and progesterone inhibits it. The maturation index, performed on
squamous cells exfoliated from the intact top layer of the surface of the vagina epithelium, is expressed as
a percentile relationship of parabasal cells to intermediate cells to superficial cells.
Useful For: Assessing hormonal status in a variety of conditions including: -assessment of ovarian
function after hysterectomy, during menstrual disorders, or in premature menses (childhood) -before,
during, and after a pregnancy (e.g., fertility studies, threatened abortion, retained placenta, hydatidiform
mole) -investigation of functioning (hormone-producing) tumors -evaluation of various endocrine
disorders -guidance for hormonal therapy
Interpretation: In the preovulatory phase of the normal menstrual cycle (peak estrogen activity),
superficial cells predominate and contain glycogen. In the postovulatory phase (peak progesterone
activity), intermediate cells predominate. Before puberty and after menopause, parabasal and intermediate
cells are seen.
Reference Values:
Descriptive report
Clinical References: 1. Naib ZM: Exfoliative cytology. Boston/Toronto, Little, Brown and
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