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Sorted By Test Name - Mayo Medical Laboratories

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FLACO<br />

57111<br />

LD_I<br />

8679<br />

receptor-targeted therapies<br />

Interpretation: An interpretive report will be provided.<br />

Reference Values:<br />

An interpretive report will be provided.<br />

Clinical References: 1. Khambata-Ford S, Garrett CR, Meropol NJ, et al: Expression of Epiregulin<br />

and Amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer<br />

patients treated with Cetuximab. J Clin Oncol 2007;25:3230-3237 2. Lievre A, Bachet JB, Le Corre D, et<br />

al: KRAS mutation status is predictive of response to Cetuximab therapy in colorectal cancer. Cancer Res<br />

2006;66(8):3992-3995 3. Spano JP, Milano G, Vignot S, Khayat D: Potential predictive markers of<br />

response to EGFR-targeted therapies in colorectal cancer. Crit Rev Oncol Hematol 2008;66:21–30<br />

Lacosamide (Vimpat)<br />

Reference Values:<br />

0.9). Use of the ratio for evaluation of patients with possible cardiovascular injury has largely been<br />

replaced by TPNT/82428 Troponin T, Serum. The LD-V form is pronounced in patients with either<br />

primary liver disease or liver hypoxia secondary to decreased perfusion, such as occurs following an MI.<br />

However, LD-V is usually not as reliable as the transaminases (eg, aspartate aminotransferase, alanine<br />

aminotransferase) for evaluating liver function. LD-V also may be elevated in muscular damage and<br />

diseases of the skin. Although it does not appear to cause or be associated with any symptoms or<br />

particular diseases, the presence of macro-LD (LD combined with an immunoglobulin) can cause an<br />

idiosyncratic elevation of total LD.<br />

Useful For: Investigating a variety of diseases involving the heart, liver, muscle, kidney, lung, and<br />

blood Differentiating heart-synthesized lactate dehydrogenase (LD) from liver and other sources As an aid<br />

in the diagnosis of myocardial infarction when used in combination with total creatine kinase (CK) and<br />

CK-MB Investigating unexplained causes of LD elevations Detection of macro-LD<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1080

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