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BHQL<br />

9738<br />

BHIS<br />

9034<br />

9172<br />

Useful For: Undetermined metabolic bone disease Renal osteodystrophy Osteomalacia Osteoporosis<br />

Paget's disease Assessing effects of therapy Identification of some disorders of the hematopoietic system<br />

Aluminum toxicity Presence of iron in the bone<br />

Interpretation: Clinical endocrinologists trained in histomorphometric techniques review and interpret<br />

the histological appearance. A pathologist interprets the bone marrow from an H & E stained slide. No<br />

histomorphometric values are given.<br />

Reference Values:<br />

The laboratory will provide an interpretive report.<br />

All results will be called to the physician designated on the Bone Histomorphometry Information Sheet.<br />

Clinical References: Recker RR: Bone Histomorphometry: Techniques and Interpretation. Boca<br />

Raton,FL, CRC Press, 1983<br />

Bone Histomorphometry, Qualitative<br />

Reference Values:<br />

The laboratory will provide an interpretive report.<br />

All results will be called to the physician designated on the Bone Histomorphometry Information Sheet.<br />

Bone Histomorphometry, Quantitative<br />

Clinical Information: Bone histomorphometry is a very sophisticated procedure utilizing full<br />

thickness bone biopsy. Techniques such as 2 time-interval labeling with tetracycline permit the direct<br />

measurement of the rate of bone formation. The information derived is useful in the diagnosis of<br />

metabolic bone diseases, including renal osteodystrophy, osteomalacia, and osteoporosis. Other<br />

information obtainable relates to disorders such as aluminum toxicity and iron abnormalities.<br />

Useful For: Undetermined metabolic bone disease Renal osteodystrophy Osteomalacia Osteoporosis<br />

Paget's disease Assessing effects of therapy Identification of some disorders of the hematopoietic system<br />

Aluminum toxicity Presence of iron in the bone<br />

Interpretation: Computer-generated histomorphometric values are given. Normal histomorphometric<br />

values for iliac crest are provided (female only). An interpretive report is provided.<br />

Reference Values:<br />

The laboratory will provide a quantitative and an interpretive report. All results will be called to the<br />

physician designated on the Bone Histomorphometry Information Sheet.<br />

Clinical References: Recker RR: Bone Histomorphometry: Techniques and Interpretation. Boca<br />

Raton, FL, CRC Press, 1983<br />

Bone Marrow Biopsy<br />

Clinical Information: Blood cells are normally produced from bone marrow. Various diseases may<br />

affect the blood cell production in the bone marrow, especially the hematologic diseases and the<br />

non-hematologic diseases involving the bone marrow. See Laboratory Screening <strong>Test</strong>s for Suspected<br />

Multiple Myeloma in Special Instructions. Also see Diagnosis and Monitoring of Multiple Myeloma in<br />

Publications.<br />

Useful For: The evaluation of the bone marrow biopsy for diagnosis of hematologic and/or non<br />

hematologic diseases<br />

Interpretation: The laboratory will provide an interpretive report of hematoxylin and eosin stained<br />

slides, iron stain, and additional stains if necessary.<br />

Reference Values:<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 285

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