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FHDLS<br />

90186<br />

FHE4<br />

57164<br />

proteins) followed by respiratory disease (rhinitis and asthma) in older children and adults due to<br />

sensitivity to inhalant allergens (dust mite, mold, and pollen inhalants).<br />

Useful For: <strong>Test</strong>ing for IgE antibodies may be useful to establish the diagnosis of an allergic disease<br />

and to define the allergens responsible for eliciting signs and symptoms. <strong>Test</strong>ing also may be useful to<br />

identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm<br />

sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of<br />

allergic reactions to insect venom allergens, drugs, or chemical allergens.<br />

Interpretation: Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased<br />

likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be<br />

responsible for eliciting signs and symptoms. The level of IgE antibodies in serum varies directly with the<br />

concentration of IgE antibodies expressed as a class score or kU/L.<br />

Reference Values:<br />

Class IgE kU/L Interpretation<br />

0 Negative<br />

1 0.35-0.69 Equivocal<br />

2 0.70-3.49 Positive<br />

3 3.50-17.4 Positive<br />

4 17.5-49.9 Strongly positive<br />

5 50.0-99.9 Strongly positive<br />

6 > or =100 Strongly positive Reference values<br />

apply to all ages.<br />

Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by<br />

Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders<br />

Company, 2007, Chapter 53, Part VI, pp 961-971<br />

HDL Cholesterol Subclasses<br />

Reference Values:<br />

HDL-2 cholesterol: 9-38 mg/dL<br />

HDL-3 cholesterol: 22-35 mg/dL<br />

<strong>Test</strong> Performed <strong>By</strong>: Quest Diagnostics/Nichols Institute<br />

33608 Ortega Highway<br />

San Juan Capistrano, CA 92690<br />

HE4<br />

Reference Values:<br />

Reference Values:<br />

Adult females: < 115 pmol/L<br />

HE4 Assay Manufacturer: Fujirebio Diagnostics<br />

Methodology: Enzyme Immunometric Assay<br />

Assay Sensitivity: 15 pmol/L<br />

HE4 values obtained with different assay methods or kits cannot be used interchangeably. Results cannot<br />

be interpreted as absolute evidence of the presence or absence of malignant disease.<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 856

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