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CDRU<br />

60156<br />

CAFF<br />

8754<br />

years) is the typical presentation. Breathing the fumes of cadmium vapors leads to nasal epithelial<br />

deterioration and pulmonary congestion resembling chronic emphysema. The most common source of<br />

chronic exposure comes from spray painting of organic-based paints without use of a protective breathing<br />

apparatus; auto repair mechanics represent a susceptible group for cadmium toxicity. In addition, another<br />

common source of cadmium exposure is tobacco smoke.<br />

Useful For: Detecting exposure to cadmium, a toxic heavy metal<br />

Interpretation: Normal blood cadmium is or =16 years: 0.0-1.3 mcg/L<br />

Clinical References: 1. deBurbure C, Buchet J-P, Leroyer A, et al: Renal and Neurologic Effects of<br />

Cadmium, Lead, Mercury, and Arsenic in Children: Evidence of Early Effects and Multiple Interactions at<br />

Environmental Exposure Levels. Environ Health Perspect 2006;114:584-590 2. Schulz C, Angerer J,<br />

Ewers U, et al: Revised and new reference values for environmental pollutants in urine or blood of<br />

children in Germany derived from the German Environmental Survey on Children 2003-2006(GerESIV).<br />

Int J Hyg Environ Health 2009;212:637-647 3. Occupational Safety and Health Administration, US<br />

Department of Labor: Cadmium Exposure Evaluation. Updated 9/2/2008. Available from URL:<br />

osha.gov/SLTC/cadmium/evaluation.html<br />

Caffeine, Serum<br />

Clinical Information: Caffeine is used to treat apnea that occurs in newborn infants, the most<br />

frequent complication seen in the neonatal nursery. Caffeine is administered orally (nasogastric tube) as a<br />

loading dose of 3 mg/kg followed by a maintenance dose of 1 mg/kg administered once every 24 to 48<br />

hours, depending on the patient's response and the serum level. In neonates, caffeine has a half-life that<br />

ranges from 20 to 100 hours, which is much longer than in adults (typically 4-6 hours) due to the<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 332

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