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FLEP<br />

91339<br />

LEPTO<br />

9697<br />

allergic reactions to insect venom allergens, drugs, or chemical allergens.<br />

Interpretation: Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased<br />

likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be<br />

responsible for eliciting signs and symptoms. The level of IgE antibodies in serum varies directly with the<br />

concentration of IgE antibodies expressed as a class score or kU/L.<br />

Reference Values:<br />

Class IgE kU/L Interpretation<br />

0 Negative<br />

1 0.35-0.69 Equivocal<br />

2 0.70-3.49 Positive<br />

3 3.50-17.4 Positive<br />

4 17.5-49.9 Strongly positive<br />

5 50.0-99.9 Strongly positive<br />

6 > or =100 Strongly positive Reference values<br />

apply to all ages.<br />

Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by<br />

Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders<br />

Company, 2007, Chapter 53, Part VI, pp 961-971<br />

Leptin<br />

Reference Values:<br />

Units: ng/mL<br />

Age Range<br />

Adults (BMI=22)<br />

Males 0.7 - 5.3<br />

Females 3.3 - 18.3<br />

Contact laboratory for other BMI reference ranges.<br />

<strong>Test</strong> Performed <strong>By</strong>: Esoterix Endocrinology<br />

4301 Lost Hills Road<br />

Calabasas Hills, CA 91301<br />

Leptospira Antibody, Serum<br />

Clinical Information: Leptospirosis is a zoonotic disease of worldwide prevalence. Although wild<br />

mammals are the primary natural reservoir of pathogenic strains, domestic animals represent a major<br />

source of human infection. Most often, transmission is indirect-by human contact with soil, food, or water<br />

contaminated by urine from an infected animal. The clinical manifestations of leptospirosis are variable,<br />

ranging from a mild infection with fever, chills, headache, conjunctivitis, myalgia, and gastrointestinal<br />

symptoms to icteric disease with severe kidney and liver involvement. Leptospira organisms may be<br />

found in the blood at the onset of disease and may persist for approximately 1 week. The organisms also<br />

may be found in the urine after week one of the disease. They may persist in the urine for 2 to 3 months;<br />

however, shedding may be intermittent and the numbers of organisms present may be low. Urine must be<br />

cultured immediately because the organisms cannot survive in acidic urine for more than a few hours.<br />

Leptospirosis is accompanied by a brisk antibody response.<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1103

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