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Sorted By Test Name - Mayo Medical Laboratories

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LVZV<br />

81241<br />

FVEGF<br />

91765<br />

VIP<br />

8150<br />

Negative (reported as positive or negative)<br />

Clinical References: 1. Kennedy PG: Latent varicella-zoster virus is located predominantly in<br />

neurons in human trigeminal ganglia. Proc Natl Acad Sci USA 1998;95:4658-4662 2. McPherson RE:<br />

Herpes zoster ophthalmicus and the immunocompromised host: a case report and review. J Am Optom<br />

Assoc 1997;68:527-538 3. Papanicolaou GA, Meyers BR, Fuchs WS, et al: Infectious ocular<br />

complications in orthotopic liver transplant patients. Clin Infect Dis 1997;24:1172-1177 4. Flamholc L:<br />

Neurological complications in herpes zoster. Scand J Infect Dis 1996;100:35-40<br />

Varicella-Zoster Virus, Molecular Detection, PCR<br />

Clinical Information: Varicella-zoster virus (VZV) causes both varicella (chickenpox) and herpes<br />

zoster (shingles). VZV produces a generalized vesicular rash on the dermis (chickenpox) in normal<br />

children, usually before 10 years of age. After primary infection with VZV, the virus persists in latent<br />

form and may emerge (usually in adults 50 years of age and older) clinically to cause a unilateral<br />

vesicular eruption, generally in a dermatomal distribution (shingles).<br />

Useful For: Rapid (qualitative) detection of varicella-zoster virus DNA in clinical specimens for<br />

laboratory diagnosis of disease due to this virus<br />

Interpretation: Detection of varicella-zoster virus DNA in clinical specimens supports the clinical<br />

diagnosis of infection due to this virus.<br />

Reference Values:<br />

Not applicable<br />

Clinical References: 1. Cinque P, Bossolasco S, Vago L, et al: Varicella-zoster virus (VZV) DNA in<br />

cerebrospinal fluid of patients infected with human immunodeficiency virus: VZV disease of the central<br />

nervous system or subclinical reactivation of VZV infection? Clin Infect Dis 1997;25(3):634-639 2.<br />

Brown M, Scarborough M, Brink N, et al: Varicella zoster virus-associated neurological disease in<br />

HIV-infected patients. Int J STD AIDS 2001;12(2):79-83 3. Studahl M, Hagberg L, Rekabdar E,<br />

Bergstrom T: Herpesvirus DNA detection in cerebrospinal fluid: differences in clinical presentation<br />

between alpha-, beta-, and gamma-herpesviruses. Scand J Infect Dis 2000;32(3):237-248 4. Iten A,<br />

Chatelard P, Vuadens P, et al: Impact of cerebrospinal fluid PCR on the management of HIV-infected<br />

patients with varicella-zoster virus infection of the central nervous system. J Neurovirol<br />

1999;5(2):172-180<br />

Vascular Endothelial Growth Factor (VEGF), ELISA<br />

Reference Values:<br />

VEGF: 31 – 86 pg/mL<br />

This test was performed using a kit that has not been approved or cleared by the FDA. The analytical<br />

performance characteristics of this test have been determined by Quest Diagnostics Nichols Institute. This<br />

test should not be used for diagnosis without confirmation by other medically established means.<br />

<strong>Test</strong> Performed by: Quest Diagnostics Nichols Institute<br />

33608 Ortega Highway<br />

San Juan Capistrano, CA 92690-6130<br />

Vasoactive Intestinal Polypeptide (VIP), Plasma<br />

Clinical Information: Vasoactive intestinal polypeptide (VIP) was originally isolated from porcine<br />

small intestine and was recognized by its potent vasodilator activity. This brain/gut hormone has<br />

widespread distribution and is present in neuronal cell bodies localized in the central nervous system,<br />

digestive, respiratory, and urogenital tracts, exocrine glands, and thyroid and adrenal glands. VIP has a<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 1840

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