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Sorted By Test Name - Mayo Medical Laboratories

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FFLT3<br />

57493<br />

FFLUC<br />

91996<br />

FLUCO<br />

82522<br />

recurrence of ventricular tachycardia. Flecainide is eliminated from blood by hepatic metabolism as well<br />

as renal clearance; significant changes in either organ system will cause impaired clearance. During<br />

preclinical trials, patients with congestive heart failure were observed to have radically altered clearance<br />

properties. Cardiac toxicity attributed to flecainide is related to its cardiac conduction slowing properties.<br />

Excessive prolongation of PR, QRS, and QT intervals occurs with increased amplitude of the T wave.<br />

Reductions in myocardial rate, contractility, as well as conduction disturbances, are also associated with<br />

excessive dose and plasma concentration of flecainide. Death can occur from hypotension, respiratory<br />

failure, and asystole. Flecainide is contraindicated in patients with sick sinus syndrome. It causes sinus<br />

bradycardia, sinus pause, or sinus arrest.<br />

Useful For: Optimizing dosage Assessing toxicity Monitoring compliance<br />

Interpretation: Flecainide is most effective in premature ventricular contractions suppression at<br />

plasma concentrations in the range of 0.2 to 1.0 mcg/mL. Plasma concentrations >1.0 mcg/mL are<br />

associated with a high rate of cardiac adverse experiences such as conduction defects or bradycardia.<br />

Therapeutic concentration: 0.2 to 1.0 mcg/mL.<br />

Reference Values:<br />

0.2-1.0 mcg/mL<br />

Clinical References: Josephson ME, Buxton AE, Marchlinski FE: The tachyarrhythmias:<br />

tachycardias. In Harrison's Principles of Internal Medicine. 12th edition. Edited by JD Wilson, E<br />

Braunwald, KJ Isselbacher, et al: New York, McGraw-Hill Book Company, 1991, p 915<br />

FLT3 Mutation <strong>Test</strong>ing<br />

Reference Values:<br />

Negative<br />

<strong>Test</strong> Performed by: Laboratory for Personalized Molecular Medicine<br />

6330 Nancy Ridge Drive, Suite 106<br />

San Diego, CA 92121<br />

Fluconazole (Diflucan)<br />

Reference Values:<br />

<strong>Test</strong> Performed by: U.T. Health Science Ctr San Antonio<br />

7703 Floyd Curl Drive<br />

Department of Pathology<br />

Fungal Lab<br />

San Antonio, TX 78229-3900<br />

Fluconazole, Serum<br />

Clinical Information: Fluconazole (Diflucan) is a synthetic triazole antifungal agent for either<br />

intravenous or oral administration. It is indicated for treatment of fungal infections caused by Candida<br />

albicans and meningitis caused by Cryptococcus neoformans. Fluconazole is

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