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Sorted By Test Name - Mayo Medical Laboratories

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PDSU<br />

88760<br />

Instructions.<br />

Useful For: Detection and identification of prescription or OTC drugs frequently found in drug<br />

overdose or used with a suicidal intent This test is designed to identify drugs present in the sample.<br />

Quantification of identified drugs, when available, may be performed upon client request.<br />

Interpretation: The drugs we know can be detected by this test are listed in Prescription and<br />

Over-the-Counter (OTC) Drug Screens Table 1 in Special Instructions. Drugs of toxic significance that<br />

are not detected by this test are: digoxin, lithium, many drugs of abuse/illicit drugs, some<br />

benzodiazepines, and most opiates. The pharmacology of each drug determines how the test should be<br />

interpreted. A detailed discussion of each drug is beyond the scope of this text. If you wish to have a<br />

report interpreted, please call <strong>Mayo</strong> <strong>Medical</strong> <strong>Laboratories</strong> and ask for a Toxicology Consultant. <strong>Mayo</strong><br />

<strong>Medical</strong> <strong>Laboratories</strong> will only report reference ranges that we have determined to be clinically correlated.<br />

Other reference ranges are available from the literature, but since we have not validated them, we choose<br />

not to report them. We will gladly discuss them during a consultation and provide reference citations if<br />

requested. Each report will indicate the drugs identified. Quantitation will only be performed upon client<br />

request.<br />

Reference Values:<br />

None detected<br />

Clinical References: Porter WH: Clinical toxicology. In Tietz Textbook of Clinical Chemistry and<br />

Molecular Diagnostice. 4th edition. Edited by CA Burtis, ER Ashwood. DE Bruns St. Louis, MO,<br />

Elsevier Saunders, 2006, pp 1287-1369<br />

Drug Screen, Prescription/OTC, Urine<br />

Clinical Information: This test looks for a broad spectrum of prescription and over-the-counter<br />

(OTC) drugs. It is designed to detect drugs that have toxic effects, as well as known antidotes or active<br />

therapies that a clinician can initiate to treat the toxic effect. The test is intended to help physicians<br />

manage an apparent overdose or intoxicated patient, to determine if a specific set of symptoms might be<br />

due to the presence of drugs, or to evaluate a patient who might be abusing these drugs intermittently. The<br />

test is not designed to screen for intermittent use of illicit drugs. Drugs of toxic significance that are not<br />

detected by this test are: digoxin, lithium, and many drugs of abuse/illicit drugs, some benzodiazepines,<br />

and some opiates. See Prescription and Over-the-Counter (OTC) Drug Screens Table 2 in Special<br />

Instructions.<br />

Useful For: The qualitative detection and identification of prescription or over-the-counter drugs<br />

frequently found in drug overdose or used with a suicidal intent. This test is designed to provide, when<br />

possible, the identification of all drugs present.<br />

Interpretation: The drugs that can be detected by this test are listed in Prescription and<br />

Over-the-Counter (OTC) Drug Screens Table 2 in Special Instructions. Positive results are definitive.<br />

Drugs of toxic significance that are not detected by this test include digoxin, lithium, many drugs of<br />

abuse/illicit drugs, some benzodiazepines, and some opiates. For these drugs, see <strong>Mayo</strong> <strong>Medical</strong><br />

<strong>Laboratories</strong>†drug abuse surveys or drug screens or individual tests. A detailed discussion of each<br />

drug detected is beyond the scope of this text. Each report will indicate the drugs identified. If a clinical<br />

interpretation is required, please request a Drug/Toxicology Lab consult (<strong>Mayo</strong> Clinic patients) or contact<br />

<strong>Mayo</strong> Laboratory Inquiry (<strong>Mayo</strong> <strong>Medical</strong> <strong>Laboratories</strong> clients).<br />

Reference Values:<br />

Identification<br />

Clinical References: 1. Tietz Textbook of Clinical Chemistry. 3rd edition. Edited by CA Burtis, ER<br />

Ashwood. Philadelphia, WB Saunders Company 1999, pp 913-917 2. Disposition of Toxic Drugs and<br />

Chemicals in Man. 5th edition. Edited by RC Baselt, RH Cravey. Foster City, CA, Chemical Toxicology<br />

Institute, 2000<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 641

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